New treatment options for acute coronary syndromes.

TitleNew treatment options for acute coronary syndromes.
Publication TypeJournal Article
Year of Publication2006
JournalThe American journal of managed care
Volume12
Issue16 Suppl
PaginationS435-43
Date Published2006 Dec
ISSN1088-0224
AbstractComplications from atherosclerotic coronary artery disease are the principal cause of death worldwide. Many therapeutic strategies have been developed to reduce the burden of this disease. Systemic antithrombotic therapy, typically with unfractionated heparin, has long been a mainstay in the management of acute coronary syndromes (ACS) despite several limitations, including intravenous administration and unpredictable pharmacokinetics necessitating frequent monitoring. In recent years, newer agents without these limitations have been developed and evaluated in clinical trials. This review focuses on novel antithrombotic therapies for ACS, particularly fondaparinux sodium, a synthetic inhibitor of clotting factor Xa.
URLhttp://www.ajmc.com/pubMed.php?pii=3252
PubMed Linkhttp://www.ncbi.nlm.nih.gov/pubmed/17203988?dopt=Abstract
Short TitleAm J Manag Care