When Minutes Matter, UK's Level-1 Pediatric and Adult Trauma Centers

Posted: 3/15/2018
Car crashes,  motorcycle accidents, falls from a rooftop or a cliff,  gunshot wounds and even injuries from tornadoes.  These are some of the types of incidents that can lead to being rushed to the hospital. And while nearly every hospital has an emergency room, a very serious injury may require a trauma center that offers more complex care – a difference that when minutes matter, could mean life or death.  Earlier this year, University of Kentucky Chandler Hospital received re-verification as a Level-1 Trauma Center and as a Level-1 Pediatric Trauma Center by the Verification Review Committee (VRC) with the Committee on Trauma of the American College of... FULL STORY
Tags: Trauma, Pediatric

St. Elizabeth Healthcare Joins Markey Affiliate Network

Posted: 3/5/2018
St. Elizabeth Healthcare announced Friday that it has joined the Markey Cancer Center Affiliate Network, further expanding its relationship with the University of Kentucky.The UK Markey Cancer Center is the only National Cancer Institute-designated cancer center in Kentucky. By joining the UK Markey Cancer Center Affiliate Network, St. Elizabeth Healthcare will now be able to further enhance care available to patients in Northern Kentucky, while allowing patients to stay closer to home and their support systems for most treatments.“We are proud to team up with the University of Kentucky Markey Cancer Center, which is recognized as one of the leading cancer care and... FULL STORY
Tags: Markey Cancer Center, Clinical

Training Kentucky's Next Generation of Cancer Fighters

Posted: 3/5/2018
For Carrigan Wasilchenko – and so many others hailing from Eastern Kentucky – cancer is not just a public health issue. It's also a problem that hits far too close to home. "I don't think I know one person who doesn't know someone who's been affected by cancer in some way," said Wasilchenko, whose mother and grandmother both had cancer. "It's very personal."Kentucky has the unfortunate distinction of being ranked first in the nation in overall cancer incidence and mortality, with the greatest disparity falling in the Appalachian region of the state. Additionally, the region faces other issues compounding the problem, including lower education rates and a lower... FULL STORY

Registration, Abstract Submission Available for Appalachian Research Day

Posted: 2/27/2018
University of Kentucky researchers and doctors work closely with communities throughout Appalachia to learn more about health issues and improve wellbeing. Appalachian Research Day, led by the UK Center of Excellence in Rural Health, is an opportunity to highlight community-based research that begins at the local level and builds upon relationships between people, neighborhoods, and groups who have common interests and concerns. The event will be held April 18 at the First Federal Center of the Hazard Community and Technical College. Abstracts to be considered for poster presentations are due March 12, and registration is due April 6.The fourth annual... FULL STORY
Tags: Center of Excellence in Rural Health, Appalachian Kentucky, Research

New Study Shows Repurposing Leukemia Drugs May Prevent Melanoma Metastasis

Posted: 2/26/2018
Data from a new study led by University of Kentucky Markey Cancer Center researchers shows that repurposing drugs used to treat leukemia has promise for preventing melanoma metastasis.Published in Science Signaling, the study showed new evidence linking the activation of ABL kinases – cancer-promoting genes – to the secretion of pro-metastatic cathepsins in melanoma. Cathepsins are enzymes that degrade proteins and are highly expressed in cancer cells, resulting in their release into the environment between the cells. These enzymes "chew up" the fibrous matrix around tumors, which allows them to get into the blood stream and lymphatic system and spread around... FULL STORY
Tags: Pharmacology and Nutritional Sciences, Research

Are Humans 'Smeller Underachievers?' Not So Fast…

Posted: 2/26/2018
Historically speaking, smell is the Rodney Dangerfield of the human senses. A series of scientific mischaracterizations rooted in (of all things) the religious politics of 19th century France and perpetuated by scientists like Sigmund Freud led to widespread acceptance that humans were underachievers in the smelling category. But a growing number of scientists are rewriting the script, advancing the argument that smell has a powerful influence on emotions and behavior. "We all have heard the hypothetical question, 'Would you rather lose your eyesight or your sense of smell?'" said John McGann, an associate professor at Rutgers University. "Most people would rather... FULL STORY
Tags: Physiology, Research

People Behind Our Research: Sally Ellingson Uses Big Data and Machine

Posted: 2/26/2018
From childhood excellence in art and math, Sally Ellingson has built a robust career in computational drug discovery. The graduate of joint program with the University of Tennessee and Oakridge National Laboratory, Ellingson is an assistant professor of biomedical informatics in the UK College of Medicine and manages high-performance computing for the UK Markey Cancer CenterCancer Research Informatics Shared Resource Facility.A central aim of her research is to increase the accuracy of predicting whether or not a drug will bind to a protein, which is useful across the board of drug development.“With machine learning, you can add biomedical big... FULL STORY
Tags: Research

How is an Olympian's Heart Different?

Posted: 2/19/2018
It's common knowledge that exercise is good for our muscles. Regular workouts help tone the muscle we have and build more muscle on top of that.But the heart is a muscle too. When you exercise, your heart "remodels" to accommodate the body's increased demand for more oxygen-rich blood to feed those muscles. But does this remodeling affect Olympic athletes differently?Not exactly, says Dr. Vincent Sorrell at the University of Kentucky Gill Heart and Vascular Institute. "Anyone who exercises regularly will likely have some remodeling to their heart, which a layperson can see reflected in their resting heart rate," he says.  "But serious amateur and... FULL STORY
Tags: Gill Heart Institute, Saha Cardiovascular Research Center

'Healthy Hearts for Women' Spotlights Cardiovascular Research

Posted: 2/14/2018
In a society that values gender equality, it's important to remember that there are differences between the sexes that directly impact health.One area in critical need of further study is cardiovascular health. For the past four years, two junior faculty at the University of Kentucky have invested their efforts to host a symposium where outstanding scientists from UK and universities across the country present new scientific advances in women's heart health and explore translational cardiovascular research areas that merit further study.The Fourth Annual Healthy Hearts for Women Symposium, held on Feb. 2, 2018, was the brainchild of Analia Loria and Frédérique... FULL STORY
Tags: Pharmacology and Nutritional Sciences, Saha Cardiovascular Research Center, Research

Markey Launches Precision Medicine Clinic, Expands Catalog of Early Phase

Posted: 2/12/2018
In its ongoing efforts to offer Kentuckians the latest, most innovative cancer treatments available, the University of Kentucky Markey Cancer Center recently launched the Precision Medicine Clinic, a new space dedicated to providing patients with increased access to phase I and phase II clinical trials. Before a new drug can be approved by the Food and Drug Administration (FDA) for widespread use, it must first be proven safe and effective in clinical trials. When patients are enrolled in phase I trials, they are often among the first people to receive a promising new drug or treatment. Phase II trials build on the information gathered in a phase I trial and often... FULL STORY
Tags: Markey Cancer Center

Olympic Team Doctor Now Serves Patients at UK HealthCare

Posted: 2/8/2018
Every four years, people around the world gather around the television and spend two weeks watching a lifetimes worth of work play out. For the hundreds of athletes that comprise Team USA, the result of their blood, sweat and tears makes us feel pride, in our country and in our fellow countrymen. While the athletes take center stage there’s a team of people in the shadows treating pain, nursing illnesses and in some cases consoling athletes.The team physicians at each Olympic games are often unsung and invisible heroes. They provide all types of treatment for the 600 athletes participating. From food poisoning to cortisone shots, doctors and athletic... FULL STORY
Tags: Orthopaedic Surgery & Sports Medicine

Join 'Markey Women Strong' to Advance Cancer Research at UK

Posted: 2/7/2018
The Markey Cancer Foundation invites you to take an active role in furthering life-changing cancer research at the University of Kentucky Markey Cancer Center through the Markey Women Strong program.Markey Women Strong is a philanthropy group comprised of women and men, who together, make a meaningful difference in cancer research by funding female researchers focused on groundbreaking cancer research at the UK Markey Cancer Center. Members donate $1,000 annually and vote for two winners each year to receive the Distinguished Researchers award. Each recipient will receive a $50,000 grant to advance their work.“The best hope a cancer patient has is good research," said... FULL STORY
Tags: Markey Cancer Center