Recent News

UK Researchers Awarded Grant to Study Aggressive Cancer Metastasis

Posted: 2/25/2015

The National Cancer Institute recently awarded a two-year, $357,743 grant to University of Kentucky Markey Cancer Center researchers to study the role of a certain protein in aggressive cancer metastasis.

The lab of Kathleen O'Connor, professor in UK's Department of Molecular and Cellular Biochemistry, studies how tumor cells interact with their environment to make cancer more aggressive.

Specifically, O'Connor's lab studies a protein called integrin α6β4, a protein that integrates signals from its environment so that cells can respond properly and die off if they are in the wrong context. This protein can cause carcinoma cells to take on some of the worst properties of cancer, including invasion, metastasis and drug resistance.

The integrin can selectively increase the expression of genes that cause cells to become particularly invasive and metastatic through a process known as DNA demethylation, but O'Connor says they do not yet know how these specific genes can be regulated.

"Through this study, we expect that understanding how the integrin affects this process will tell us more about how specific DNA demethylation occurs, as well as how cancers can become more invasive without mutating the DNA," O'Connor said.


Tags: Markey Cancer Center, Grants and Funding

Gill Heart Institute Selected for Major Clinical Trial for

Posted: 2/24/2015
The Gill Heart Institute at the University of Kentucky is participating in a multi-center clinical trial of a new medical device that has the potential to improve the outcomes and reduce the incidence of angina for patients with coronary artery disease (CAD). For decades, cardiologists opened blocked coronary arteries using balloons and followed that by implanting stents (mesh-like devices) that act... FULL STORY
Tags: Gill Heart Institute, Clinical Trials

UK Alumni Association Honors Great Teachers

Posted: 2/23/2015
On Saturday, the University of Kentucky Alumni Association presented its 2015 Great Teacher Awards to six recipients at a recognition dinner. The award-winners were then recognized on the court of Rupp Arena during the Kentucky vs. Auburn men’s basketball game. The recipients are: Sameer Desai, College of Medicine, Emergency Medicine Pearl James, College of Arts and Sciences, English W. Brent Seales... FULL STORY
Tags: Faculty, Awards and Recognition

UK HealthCare Receives State Approval to Add 120 Patient Beds

Posted: 2/19/2015 - Tags: UK HealthCare
UK HealthCare has received approval from the Kentucky Cabinet for Health and Family Services Division of Certificate of Need to add 120 patient beds. The application for the Certificate of Need to increase the number of licensed beds was filed in October 2014 and notice of approval has been received. "This approval allows us to move forward in our strategic plan and further our mission to take care of patients throughout the Commonwealth who need our advanced subspecialty care and destination services," said Dr. Michael Karpf, University of Kentucky vice president for health affairs. UK HealthCare’s previous licensing was for 825 beds but after experiencing... FULL STORY

CCTS Funds Pilot Awards for High Impact Studies, Junior Faculty, and

Posted: 2/16/2015
The University of Kentucky Center for Clinical and Translational Science has awarded 12 pilot grants to support innovative, collaborative research relevant to the health challenges and disparities faced by the nation and the citizens of Kentucky. Such preliminary and proof-of-concept studies are critical to moving basic laboratory findings into clinical applications. The CCTS pilot grant funding program prioritizes development of enabling new technologies, therapeutics, and diagnostics, as well as novel cross-disciplinary collaborative programs that address the health and health care needs of the people of Appalachia. Pilot investigators benefit... FULL STORY

Registration Now Being Accepted for Annual Multicultural Health Careers

Posted: 2/16/2015 - Tags: Multicultural Health Careers, Open House
The University of Kentucky is pleased to announce that registrations for the 8th Annual Multicultural Health Careers Open House is now open. This year’s Open House is on Saturday, April 25, 2015, from 9:30 a.m. to 4 p.m. Any high school, undergraduate, or graduate student is encouraged to attend if they are interested in pursuing a health-related program at UK. The annual event is sponsored by the University of Kentucky’s Health Colleges Student Diversity Services (HCSDS) in conjunction with UK’s six health colleges. The Multicultural Health Careers Open House continues the University's commitment to building diversity by targeting traditionally... FULL STORY

UK Fellowship Program Accredited by the American Board of Addiction

Posted: 2/12/2015 - Tags: Psychiatry, UK HealthCare
The American Board of Addiction Medicine (ABAM), located in Bethesda, Maryland, recently accredited the University of Kentucky Department of Psychiatry's Addiction Medicine Fellowship Program. There are only 27 such ABAM-accredited programs in the U.S. “We are delighted to be recognized for our excellent work in addiction medicine, which emphasizes screening, intervention, and treatment, and makes treatment more readily available to those who need it,” said Dr. Lon Hays, chair of the Department of Psychiatry in the UK College of Medicine. The Addiction Medicine Fellowship program at UK will help physicians understand the biopsychosocial framework for... FULL STORY

UK Libraries Workshops to Help Users Save Time, Be More Effective With

Posted: 2/11/2015 - Tags: Research
From undergraduate students to graduate students and faculty members, everyone can use some time-saving strategies for library research. A series of workshops presented by University of Kentucky Libraries will help members of the campus community save time and be more effective in their research. The series targets a number of specific topics from basic research skills to scholarly communication issues. The UK Libraries Workshops range from 30 minutes to 90 minutes each. Upcoming workshop offerings are: · "Open Up Your Published Research: Introduction to Open Access," 3 p.m. Wednesday, Feb. 11, at William T. Young Library, Room 1-57; · "What Your Students Think... FULL STORY

UK Research Building Clears First Legislative Hurdle

Posted: 2/11/2015 - Tags: Research
The House Appropriations and Revenue Committee Tuesday strongly endorsed legislation that would provide funding for a multi-disciplinary research building on the University of Kentucky campus targeted at the Commonwealth’s most pressing challenges. “Our goal is to make death a beggar in Kentucky,” said UK President Eli Capilouto, who testified before the committee Tuesday morning. The legislation now goes to the full House for consideration. Specifically, the state would fund $132.5 million of the projected $265 million research building. UK would fund the other half. The building, which would be located on South Limestone next to the bio-pharmacy building,... FULL STORY

Echocardiography is Much More Than Just "Taking Pictures"

Posted: 2/11/2015
 It wasn't so long ago that the only imaging available to physicians was an X-ray.  How times have changed. The term "imaging" now applies to any number of procedures, including MRI, CT scans, sonography, and echocardiography, all of which help physicians diagnose patient illnesses non-invasively.  As director of the echocardiography lab at the University of Kentucky's Gill Heart Institute, Dr. Mikel Smith excels at the latter. "We like to joke that we take pictures for a living," Dr. Smith says of himself and his team.  "Of course there are M.D.s, but the team is much broader than that," Dr. Smith says. "From the clerks who check our patients in,... FULL STORY

Clinical Neuroscience Winter Expo Set for March 6-7

Posted: 2/10/2015 - Tags: Neuroscience
The University of Kentucky's Kentucky Neuroscience Institute, Office of Clinical Simulation, and the UK HealthCare/Norton Healthcare Stroke Care Network have joined forces to offer a new kind of symposium for neuroscience and stroke care. The Clinical Neuroscience Winter Expo, set for March 6 and 7, will be an informative, interactive event exploring the latest advancements in the neurosciences and stroke care. "We wanted this to be very different from traditional symposia, so the Expo was designed to be highly interactive," said Dr. Michael Dobbs, director of UK HealthCare's Stroke Network. "Through the use of interactive learning methods and patient simulation... FULL STORY

UK Chandler Hospital Hosts First National Wear Red Day Symposium

Posted: 2/9/2015
Women spotted in red at the University of Kentucky Chandler Hospital on Feb. 6 aren't celebrating Valentine's Day early. Rather, they're signifying their support of heart health awareness as part of National Wear Red Day, celebrated on the first Friday of every February, and the inaugural National Wear Red Day Symposium. Sponsored by the Department of Pharmacology and Nutritional Sciences, the symposium brings together UK HealthCare experts from pharmacology and nutrition, cardiology, the Gill Heart Institute, and internal medicine to discuss the impact of heart disease on women. According to the American Heart Association, heart disease or stroke account for the... FULL STORY

UK Neonatologist's Study Trial Supports Alternative Therapy for Drug-

Posted: 2/2/2015 - Tags: Research, Pediatrics
In the past decade, the number of Kentucky babies starting life with a drug dependency, or neonatal abstinence syndrome (NAS), has skyrocketed from 1.3 per 1,000 births to 19 per 1,000 births. Just like adults coming off drugs, babies whose mothers used opiate drugs during pregnancy, will suffer from a number of withdrawal symptoms, including tremors and irritability. The most common form of treatment for babies suffering from withdrawal is the opiate morphine, which can hinder brain development during a critical growth period in a baby's life. The treatment period for infants requires hospitalization and can last weeks or even months, resulting in high... FULL STORY

Markey Launches New Research Network, Expanding Collaboration in Clinical

Posted: 2/2/2015
The University of Kentucky Markey Cancer Center has announced that St. Mary’s Regional Cancer Center in Huntington, W.Va., is the first member of the Markey Cancer Center Research Network, a newly launched initiative conducting high priority cancer research through a network of collaborative centers with expertise in the delivery of cancer care and conduct of research studies. Thousands of patients across Eastern Kentucky and West Virginia will have close-to-home access to innovative clinical research studies in the treatment and epidemiology of cancer as well as research studies in the prevention and early detection of cancer. The team at St. Mary’s Regional Cancer... FULL STORY

Registration Now Available for UK Barnstable Brown Obesity & Diabetes

Posted: 2/2/2015 - Tags: Research, Barnstable Brown Obesity and Diabetes Research Day
Registration is now available for the fifth annual Barnstable Brown Obesity... FULL STORY