Recent News

UK Critical Care Survivors Clinic Benefits Patients While Reducing Readmissions

Posted: 11/24/2015

Darrell Raikes waved sleepily to his wife as they wheeled him down to the operating room for a routine knee replacement last May.

He woke up in the Critical Care Unit four weeks later.

Darrel had an adverse reaction to his anesthesia and began bleeding into his lungs post-operatively. Dr. Ashley Montgomery, Darrell's critical care physician, had to navigate tricky territory: the drugs that are standard care to prevent blood clots post-knee replacement would also contribute to Darrell's bleeding.

"We like to think that medicine is an exact science, but there often isn't a 'yes or no' answer to a patient's medical problems, particularly in an ICU situation where multiple organ systems are involved and the treatment for one problem is contraindicated for the patient's other problems," Montgomery said. "We talk to the patient, use the best data available and make an informed decision about how to best care for them."

Montgomery and her team in the UK HealthCare Intensive Care Unit were able to stabilize Darrell without compromising his knee replacement by inserting an inferior vena cava filter (IVC filter). This umbrella-like device catches circulating clots and prevents them from travelling to the lung. Darrell was discharged from the ICU on June 29... FULL STORY

Tags: Internal Medicine, Critical care

Nutritional Scientist Explains Cancer-Fight Potential of

Posted: 11/23/2015
Plants put up a natural defense system against bacteria and disease through bioactive chemical constituents called flavonoids. While humans have turned to plants and herbs for medicinal purposes throughout history, researchers are now learning how to harness the chemopreventive properties of flavonoids to prevent human disease. Medical research... FULL STORY
Tags: Nutritional Science, Faculty, Awards and Recognition

National Rural Health Day

Posted: 11/20/2015
The Kentucky Office of Rural Health (KORH) and the University of Kentucky Center of Excellence in Rural Health (UK CERH) joined the National Organization of State Offices of Rural Health (NOSORH) and other state/national rural stakeholders to celebrate National Rural Health Day. NOSORH created National Rural Health Day as a way to showcase rural... FULL STORY
Tags: Rural Health, Center of Excellence in Rural Health

Gensel Laboratory Awarded Grant to Study Spinal Cord Injury Repair

Posted: 11/19/2015 - Tags: Physiology, Research
The National Institute of Neurological Diseases and Stroke (NINDS) has awarded a five-year, $1.6 million grant to John C. Gensel, Ph.D., of the University of Kentucky Spinal Cord and Brain Injury Research Center (SCoBIRC), to study the potential role of the immune system in repairing spinal cord injuries. Spinal cord injuries can result in permanent paralysis. Macrophages, white blood cells involved in immune responses, migrate to wounded areas of the spinal cord following an injury, where they assume M1 (i.e. pro-inflammatory) or M2 (i.e. pro-tissue repair) functions. M2 macrophages have the potential to improve wound healing and subsequent recovery from spinal cord... FULL STORY

Cardiovascular Research Is Personal for UK's Lisa Cassis

Posted: 11/18/2015
For University of Kentucky Vice President for Research Lisa Cassis the drive to conduct meaningful research is personal.  “You don’t go into it for the money, you go into it because you want to help people,” Cassis said. The longtime UK professor chose to devote her career to cardiovascular research after watching her father battle heart disease for nearly 30 years. He suffered his first heart attack at age 51, went through three open heart surgeries, and was able to live until age 80 by managing his diet. However, Cassis says his lipid problems kept coming back no matter what he did. “I wanted to know why we aren’t able to help someone like... FULL STORY

Glen Campbell's Physician, Dr. Ron Petersen, to Speak

Posted: 11/17/2015
Many people think there's never been a darker time for Alzheimer's disease (AD). There's no cure, they point out. The field is littered with treatment failures; the last time the FDA approved a drug to treat the symptoms of Alzheimer's disease was 2003. Dr. Ronald Petersen is adamant that this is wrong-headed thinking. "We learn even in failure," he said, "and we know more than ever before about how and when the AD disease process begins." Petersen is the director of the Mayo Clinic Alzheimer's Disease Center and the Mayo Clinic Study of Aging, a population-based study of aging with a cohort of more than 2,800 men and women. The study generates a massive... FULL STORY

Kentucky LEADS Collaborative Implements Multipronged Approach to Lung

Posted: 11/16/2015 - Tags: Research
In the state with the highest incidence and mortality rates of lung cancer, a collaborative project is taking a multipronged approach to address the continuum of the disease, from prevention to screening to survivorship care. The Kentucky LEADS (Lung cancer. Education. Awareness. Detection. Survivorship) Collaborative, a joint effort of the University of Kentucky, University of Louisville and Lung Cancer Alliance, today announces details of three new statewide programs to reduce the burden of lung cancer in the Commonwealth. The project is the first of its kind to unite an interdisciplinary team of community partners and lung cancer prevention and control experts,... FULL STORY

Loria to Present Gender-Based Cardiovascular and Metabolic Research at

Posted: 11/16/2015 - Tags: Gill Heart Institute, Pharmacology, Research
Analia Loria, assistant professor of pharmacology and nutritional sciences at the University of Kentucky, will be a featured presenter at the First Physiology and Gender Conference organized by the American Physiological Society this week. At the conference, Loria will be discussing her research on the susceptibility of rodents to develop cardiovascular disease and metabolic syndrome in adulthood after being exposed to high-stress situations early in life. Loria utilizes animal models to study the effects in the cardiovascular system to mimic children that have been exposed to psychosocial stresses such as abuse, neglect, parental loss and other traumas. The stress, in... FULL STORY

Barbara Phillips Elected President of the American College of Chest

Posted: 11/13/2015 - Tags: Faculty, Awards and Recognition, Internal Medicine
Dr. Barbara Phillips, professor of pulmonary, critical care and sleep medicine in the Department of Internal Medicine at the University of Kentucky, was elected the 78th president of The American College of Chest Physicians (CHEST) effective Nov. 1, 2015. Phillips previously served as president-elect in 2014. In 1982, she became an active member of CHEST, and in 1983 advanced to Fellow. She served as editor of CHEST SEEK Sleep Medicine, working on the second, third and fourth editions. Phillips also served as Regent-at-Large for the American College of Chest Physicians for eight years. Phillips is also involved with numerous other outside organizations. She... FULL STORY

Food, Flavor and Science: Neurogastronomy Symposium Begins Pursuit of

Posted: 11/11/2015 - Tags: Physiology, research
Two women, seated at a table, told their stories in quiet tones.  A group of chefs, some standing, others seated, leaned forward eagerly, clearly interested in what these two women had to say. They peppered the women with questions: did food taste better cold or hot?  Was texture an issue? Did a glass of wine before dinner help or hurt the flavor experience? The women have both taken chemotherapy for their cancer.  One of them — Gina Mullin — will be taking chemotherapy every three weeks for the rest of her life. Both she and patient Jen Cooper tell heartbreaking stories about a side effect of chemotherapy that gets swept under the... FULL STORY

Health Matters Airs 600th Show

Posted: 11/7/2015 - Tags: Rural Health
Many physicians enjoy a round of golf as a relaxing retreat from the vigor's of a busy medical practice, but Dr. Anthony Weaver instead heads to the broadcast station of WMKY radio in Morehead where he and co-host Rick Phillips, manager of communications infrastructure at UK, co-host Health Matters, a medical news show that recently aired the 600th show since it first debuted in 2003. "It's my golf," said Weaver, a general internist and associate dean of the Rural Physician Leadership Program at the University of Kentucky College of Medicine based at a satellite campus in Morehead. "I have a passion for teaching and felt like I had lost opportunities to teach in my... FULL STORY

UK Researchers Showcase Potential Therapy for Parkinson’s Disease at

Posted: 11/4/2015 - Tags: Parkinson's disease, Research
Two University of Kentucky researchers will present evidence supporting a promising new therapy for Parkinson’s disease as part of a showcase of scientific research and innovation during the Michael J. Fox Foundation (MJFF) Parkinson’s Disease Therapeutics Conference. University of Kentucky College of Medicine professor Greg Gerhardt and associate professor Richard Grondin will today present “Therapeutic Development of siRNA Targeting Alpha-Synuclein” during the MJFF Parkinson’s Disease Therapeutics Conference in New York. The research studies whether targeting the alpha-synuclein protein is a safe approach to combating Parkinson’s disease. Gerhardt and Grondin were... FULL STORY

Ambati Lab Receives $2.4 Million Grant to Study Newly Discovered Source of

Posted: 11/1/2015 - Tags: Ophthalmology and Visual Sciences, Research
The John Templeton Foundation, a philanthropic organization devoted to rigorous scientific research and scholarship, has awarded a three-year, $2.4 million grant to Dr. Jayakrishna Ambati and his research team at the University of Kentucky Department of Ophthalmology and Visual Sciences to study the genetics of a new source of DNA they discovered. The human body is made up of trillions of cells, with their own complete set of genetic instructions. This set of instructions is known as our genome and is made up of DNA. Within this DNA is a unique chemical code that guides human growth, development and health. The Ambati lab discovered a new ecosystem of genetic... FULL STORY

$1.6 Million Grant to Sanders-Brown Researcher Will Fund Study of

Posted: 10/27/2015 - Tags: UK Sanders-Brown Center on Aging, Research
The National Institute of Neurological Disorders and Stroke (NINDS) has awarded Joe Abisambra, Ph.D., of the University of Kentucky Sanders-Brown Center on Aging a five-year, $1.6 million grant to study a group of diseases called tauopathies. Tauopathies are a group of more than 20 neurodegenerative disorders that affect nearly eight million Americans. These disorders all share one common characteristic: deposition of a protein called "tau" into sticky bundles inside brain cells. While Alzheimer's disease is the most-recognized tauopathy, Pick’s disease, and Chronic Traumatic Encephalopathy (originating from head trauma) are all a part of this expanding disease... FULL STORY

UK Begins Work on Research Facility Designed to Address State's

Posted: 10/23/2015
Flanked by Gov. Steve Beshear and legislative leaders, University of Kentucky President Eli Capilouto Friday announced the beginning of work on a research facility unique in the country — a building dedicated to addressing health challenges and disparities in Kentucky. "Today, we commence building — not for ourselves, but for the future and the health of the Commonwealth of Kentucky," Capilouto said. "We have said that it is time for death to be a beggar in Kentucky. Today, we mark in a tangible and real way our intent to deliver on that promise." The research facility — scheduled for completion in spring 2018 — is a $265 million building. Half of... FULL STORY