Recent News

Drs. Evers, Smyth discuss personalized medicine

Posted: 7/27/2015

The past decade, Dr. Mark Evers says, has been a revolution.

Thanks to advances in personalized medicine over the past 10 years, Evers says patients today receive treatments that are better tailored to their genetic makeup and specific medical history. Evers, the director of the UK Markey Cancer Center, along with Dr. Susan Smyth, director of the Gill Heart Institute, appeared Sunday on KET’s One to One to discuss personalized medicine.

“Really it has been the last 10 years, I would say, that the revolution has occurred,” Evers said. “I’ve been in this business treating patients for 20 years and now is such an exciting time to be practicing medicine, to be doing research.”

In a wide-ranging conversation with KET’s Bill Goodman, Evers and Smyth discussed how personalized medicine is changing the landscape of cancer and cardiovascular treatments.

Check out some highlights from the interview and be sure to watch the full video.

Smyth on defining personalized medicine

Personalized or precision medicine really means taking as much information about one individual as possible to be able to tailor specific treatments or preventative strategies toward them. So it’s taking their genetic information, taking information from... FULL STORY

Tags: Internal Medicine

Family Medicine Clinic Earns National Recognition

Posted: 7/24/2015
Few people think of a health care facility where they go to see their physician as a 'home,' but that's exactly the kind of environment Dr. Jonathan Ballard, medical director for the University of Kentucky's Family and Community Medicine (FCM) Clinic, and a team of health care providers strive to give every patient that walks through the clinic... FULL STORY

UK Executive Healthcare Leadership Program is Thriving

Posted: 7/23/2015
When a new program reaches its second year, it officially can be referred to as an annual event. By the time it reaches its third year, it is very likely on its way to sustained success. And, by the time that program is ready to begin its seventh year, you would have to call it 'a smash hit.' Such is the case for the Executive Healthcare... FULL STORY
Tags: UK HealthCare

Identifying Biomarkers Key to Early Intervention in Alzheimer's

Posted: 7/22/2015 - Tags: Alzheimer's research, UK Sanders-Brown Center on Aging
Although the term didn’t surface until the 1980s, the concept of biomarkers has been around for almost a century. Today, doctors routinely test blood for signs of anemia or the antigen associated with prostate cancer. Urine samples can hint at the presence of infection or diabetes, and EEGs diagnose electrical abnormalities in the brain. But scientists are now advancing the concept, looking for ways to identify a host of diseases early in the process to provide opportunity for early intervention and improve the chances that treatment will be effective. This is particularly true for Alzheimer’s disease (AD), where evidence points to the fact that the disease... FULL STORY

For One UK Doctor, Treating Patients is a Family Affair

Posted: 7/20/2015 - Tags: Faculty
To most people, a "family doctor" is who they visit when they aren’t feeling their best. For Dr. Ana Lia Castellanos, the term takes on a whole new meaning. Castellanos, a nephrologist with the University of Kentucky Transplant Center, comes from a family of physicians – her father, uncle and cousin are practicing nephrologists in her home country of Honduras. With the help of her family and some of her colleagues here at UK, she's helping develop a kidney transplant program back in Honduras. Honduras has one of the highest rates of end-stage kidney disease in Latin America, and overall kidney disease is on the rise. The country's current lack of a transplant... FULL STORY

SCoBIRC Research Published in the Journal of Neuroscience

Posted: 7/14/2015 - Tags: Reseach, scobirc
Macrophages are cellular sentinels in the body, assigned to identify “attacks” from viruses, bacteria or fungi and sound the alarm when they are present. However, these cells are a “double-edged sword” in spinal cord injury, providing both neural repair-promoting properties and pathological functions that destroy neuronal tissue “We know from previous research that macrophages are versatile, and signals at the injury site can stimulate repair or destruction—or confusingly, both,” John Gensel, Ph.D., assistant professor of physiology in the Spinal Cord and Brain Injury Research Center at the University of Kentucky, said. “But the mechanisms through which these signals... FULL STORY

Zhang to Lead New Institute of Biomedical Informatics

Posted: 7/9/2015
A new Institute of Biomedical Informatics at the University of Kentucky will integrate and leverage large data systems across the academic and medical enterprise to improve patient care, research and education. GQ Zhang, Ph.D., will join UK Aug. 1 as director of the institute. He will also serve as chief of the newly established biomedical informatics division in the UK College of Medicine and co-director of the biomedical informatics core of the UK Center for Clinical and Translational Science. The establishment of the institute and recruitment of Zhang and his research team reflect an enhanced investment in biomedical informatics across the UK campus... FULL STORY

Class of 2019 White Coat Ceremony

Posted: 7/2/2015 - Tags: White Coat Ceremony
The UK College of Medicine will hold the Class of 2019 White Coat Ceremony on Friday, July 31, 2015 at 1:30 p.m. at the Singletary Center for the Arts located at 405 Rose Street. The ceremony will include a formal presentation and donning of the incoming students first white coat by faculty and alumni, a universal symbol of compassion and humanism in medicine, in addition to a recitation of the Pledge of Professionalism.  Dean Frederick de Beer, M.D., will deliver the keynote address. The white coats are provided by the UK Medical Alumni Association. There will be a reception following the ceremony.

Gill Heart Institute Researcher Explores Stem Cell Therapy for Heart

Posted: 6/26/2015 - Tags: Gill Heart Institute
Regenerative medicine is a relatively new concept in the U.S., although research into the use of stem cells to treat disease is more established in Europe. Since stem cells have the ability to differentiate into any type of cell, they have the potential to foster the repair of damaged tissue. As such, stem cell therapy offers great promise in the development of medical treatments for a wide range of conditions — including heart attacks. "When someone has a heart attack, we shift into maintenance mode by prescribing medicines and other treatments to prevent another heart attack, but we can't reverse the damage that's already done," said Dr. Ahmed Abdel-Latif... FULL STORY

$1.6 Million Grant Looks at Role of Key Protein following Traumatic Brain

Posted: 6/24/2015 - Tags: Research, Grants and Funding, UK Sanders-Brown Center on Aging, Alzheimer's research
Linda Van Eldik, Ph.D., director of the Sanders-Brown Center on Aging at the University of Kentucky, has received a $1.6 million grant to study the role of a key protein in the cascade of events following traumatic brain injury (TBI). The five-year grant from the National Institute of Neurological Disorders and Stroke (NINDS) explores the role of a protein called p38a in the inflammatory response process post-brain injury in a mouse model of mild TBI. The research will also determine the potential for a small molecule inhibitor of p38a activity to suppress the inflammation, and thereby prevent neuron degeneration and the resulting behavioral impairments caused by... FULL STORY

COM student featured in Journal of Neuropathology & Experimental

Posted: 6/22/2015
Ese Ighodaro, a COM M.D./Ph.D. student, mentored by Pete T. Nelson, M.D., Ph.D., recently published a research article titled “Hippocampal Sclerosis of Aging Can Be Segmental: Two Cases and Review of the Literature” in the July issue of the Journal of Neuropathology & Experimental Neurology. In addition to having their work published in the journal, figures from their research will also be featured on the cover of the journal.    To view the research abstract, click here.Click here to view the cover of the July issue.  

UK Hosts 5th Annual Barnstable Brown Research Day

Posted: 6/17/2015 - Tags: Reseach, Barnstable Brown Kentucky Diabetes and Obesity Center
The University of Kentucky’s fifth annual Barnstable Brown Obesity and Diabetes Research Day was held on May 20 at the Albert B. Chandler Hospital Pavilion A. Since 2011, the event has focused on current findings in obesity and diabetes research and features presentations by nationally prominent physician-scientists as well as the work of regional researchers and UK students, postdoctoral fellows and faculty chosen from abstract submissions. President Eli Capilouto opened the day with remarks about the importance of diabetes research at UK, given the prevalence of the disease in the region and the fact that diabetes is one of the leading causes of death and disability... FULL STORY

Hoven Elected First Female Chair of World Medical Association

Posted: 6/16/2015 - Tags: Alumni
Retired University of Kentucky professor Dr. Ardis D. Hoven was elected the first female chair of the World Medical Association (WMA) at the organization’s 200th council meeting in Oslo, Norway. Hoven has served as chair of the American Medical Association delegation to the WMA for the past few years and now will serve a two-year term as chair of the WMA. The WMA is the international organization representing physicians from 111 national medical associations. “I feel fortunate to have the opportunity to do this,” Hoven said. “I see myself not so much as a woman in this role, but as a leader of a global organization of physicians who are working to support their peers... FULL STORY

Gill Heart Institute Doctor Assesses New Cholesterol Drugs

Posted: 6/12/2015 - Tags: Reseach, Gill Heart Institute
On the brink of FDA approval is a new class of cholesterol-lowering drugs with the potential to change the landscape in the prevention of heart attack and stroke. "These new drugs are a blockbuster as far as achieving the goal of getting LDL levels down markedly," Dr. Thomas Whayne, director of the Lipid Management Clinic at the Gill Heart Institute, said. "Particularly in the cases where high-risk patients cannot tolerate the current standard of care, we will have a powerful pharmaceutical alternative. It's going to be fantastic." Called PCSK9 inhibitors, these drugs appear to sharply reduce levels of bad (LDL) cholesterol. Clinical trials of PCSK9 inhibitor... FULL STORY

Four Grants in Six Months for Sanders-Brown Researcher

Posted: 6/12/2015 - Tags: UK Sanders-Brown Center on Aging, Reseach
A researcher from UK's Sanders-Brown Center on Aging has received four different grants in six months to explore both disease processes and potential treatments for Alzheimer's and related diseases. Since January of 2015, Joe Abisambra, Ph.D., assistant professor in the Department of Physiology and Sanders-Brown Center on Aging, has been awarded grants totaling more than $1.3 million from the Department of Defense, UK's Center for Clinical and Translational Science, GlaxoSmithKline, and UK's Center for Biomedical Excellence. "The overall objective of my research program is to investigate the molecular mechanisms by which tau causes neurodegeneration in diseases... FULL STORY