Understanding history, and not repeating it. Neuroprotection for acute ischemic stroke: from review to preview.

TitleUnderstanding history, and not repeating it. Neuroprotection for acute ischemic stroke: from review to preview.
Publication TypeJournal Article
Year of Publication2015
JournalClinical neurology and neurosurgery
Volume129
Pagination1-9
Date Published2015 Feb
ISSN0303-8467
AbstractNeuroprotection for ischemic stroke is a growing field, built upon the elucidation of the biochemical pathways of ischemia first studied in the 1970s. Beginning in the early 1990s, means by which to pharmacologically intervene and counteract these pathways have been sought, though with little clinical success. Through a comprehensive review of translations from laboratory to clinic, we aim to evaluate individual mechanisms of action, while highlighting potential barriers to success that will guide future research.
URLhttps://linkinghub.elsevier.com/retrieve/pii/S0303-8467(14)00456-9
DOI10.1016/j.clineuro.2014.11.013
PubMed Linkhttp://www.ncbi.nlm.nih.gov/pubmed/25497127?dopt=Abstract
Short TitleClin Neurol Neurosurg