John Scott Roth, MD, FACS

Bio / Education: 

Medical School
Medical College of Virginia

Residency
University of Kentucky

Fellowship
Minimally Invasive Surgery
University of Kentucky

Board Certification
American Board of Surgery

Surgical Interests

Minimaly Invasive and Laparoscopic Surgery

Hiatal hernia repair, Reflux Surgery, swallowing disorders - laparoscopic and open

Hernia Repair and Abdominal Wall Reconstruction - laparoscopic and open

Complex Surgery of the GI tract 

Gastrointestinal Surgery

Surgery for disorders of the spleen, adrenal gland or pancreas

Dr. J. Scott Roth explains minimally invasive surgery and hernia repair on Channel 27, WKYT.

One satisfied patient speaks up.

Dr. J. Scott Roth demonstrates an inguinal hernia repair in a teleconference sponsored by UK Area Health Education Centers (AHECs) and Kentucky Telecare. Over 200 high school students from rural and urban Kentucky were part of the conference and were able to view the surgical procedure live.

Dr. J. ScottRoth Special to the Herald-Leader
posted with permission of the Lexington Herald-Leader
Published on January 1, 2009, Page C6, Lexington Herald-Leader (KY)

Pregnancy Hernias Common
most don't need to be repaired, as surgery has some risks

Pregnancy is full of enough surprises, never mind the addition of a newly discovered bulge protruding from your belly button or groin. One of the most common reasons for an unexpected bulge during pregnancy is the development of a hernia. A hernia is simply a hole in the muscular layer of the abdominal wall, which causes intestinal or fatty tissue within the abdomen to stick out. This can cause pain and, occasionally, intestinal obstruction.

Hernias can occur as a result of any increase in abdominal pressure. While straining and lifting are most commonly associated with hernias, the pressure in your abdomen will undoubtedly increase from a growing fetus.

Hernias do not go away. Once a hernia has formed, it will remain until it has been repaired. However, not all hernias need to be repaired, particularly hernias that are not causing any symptoms. This is particularly true during pregnancy.

Most hernias diagnosed during pregnancy can be treated without surgery and if surgery is necessary in most cases it can be delayed until several months after the baby is born. In many cases, the hernia becomes less painful later in pregnancy due to the uterus blocking the hole in the muscles.

Surgeons should consider the risks of surgery in considering repair. During the first trimester, the likelihood of a miscarriage is increased with an elective operation. During the third trimester, the likelihood of pre-term labor is increased. Elective surgery should only be considered during the second trimester (months 4-6). However, the growing baby and uterus will place increased stretch and strain on the repair and could result in an early recurrence of the hernia. In general, when hernias return, they are larger than they were originally.

In general, hernias are repaired with a soft and pliable material called mesh. Mesh is sewn around the hernia to reinforce the defect in the musculature. While mesh is very strong and is designed to prevent hernias from returning, it will not stretch. If a mesh is placed during pregnancy, it may tear away from the muscles as a result of the growing uterus, resulting in a return of the hernia. This can cause significant discomfort during the remainder of pregnancy.

Minimally invasive surgical techniques can be used to repair most hernias. Three tiny incisions are made, and a small camera is placed inside of the abdomen. Patients undergoing a minimally invasive, or laparoscopic, hernia repair will have less postoperative discomfort and a quicker return to normal activities while avoiding the larger incision associated with a traditional open operation. The long-term outcomes following hernia repair are comparable between traditional open surgery and minimally invasive surgery.

Even with a hernia, a Caesarean section is not usually necessary. Almost all women can safely deliver a baby vaginally. Your obstetrician or midwife can help you throughout the delivery process to ensure that the hernia does not become a problem during delivery.

The development of a hernia during pregnancy is not uncommon. The joy of future motherhood need not be interrupted by the development of this new bulge. By working closely with your obstetrician and hernia surgeon, most hernias will not endanger your well-being or your baby’s.

Dr. J. Scott Roth is an associate professor of surgery and director of the Center for Advanced Training & Simulation (CATS) at the University of Kentucky College of Medicine.

PubMed Publications: 

  • Holihan, J.L.;Bondre, I.;Askenasy, E.P.;Greenberg, J.A.;Keith, J.N.;Martindale, R.G.;Roth, J.S.;Liang, M.K.;Ventral Hernia Outcomes Collaborative (VHOC) Writing, G. "Sublay versus underlay in open ventral hernia repair." The Journal of surgical research 202, 1 (2016): 26-32. [PubMed Link] | [ Full text ]
  • Tharappel, J.C.;Harris, J.W.;Zwischenberger, B.A.;Levy, S.M.;Puleo, D.A.;Roth, J.S. "Doxycycline shows dose-dependent changes in hernia repair strength after mesh repair." Surgical endoscopy 30, 5 (2016): 2016-21. [PubMed Link] | [ Full text ]
  • Liang, M.K.;Holihan, J.L.;Itani, K.;Alawadi, Z.M.;Gonzalez, J.R.;Askenasy, E.P.;Ballecer, C.;Chong, H.S.;Goldblatt, M.I.;Greenberg, J.A.;Harvin, J.A.;Keith, J.N.;Martindale, R.G.;Orenstein, S.;Richmond, B.;Roth, J.S.;Szotek, P.;Towfigh, S.;Tsuda, S.;Vaziri, K.;Berger, D.H. "Ventral Hernia Management: Expert Consensus Guided by Systematic Review." Annals of surgery (2016): [PubMed Link] | [ Full text ]
  • Holihan, J.L.;Askenasy, E.P.;Greenberg, J.A.;Keith, J.N.;Martindale, R.G.;Roth, J.S.;Mo, J.;Ko, T.C.;Kao, L.S.;Liang, M.K.;Ventral Hernia Outcome Collaboration Writing, G. "Component Separation vs. Bridged Repair for Large Ventral Hernias: A Multi-Institutional Risk-Adjusted Comparison, Systematic Review, and Meta-Analysis." Surgical infections 17, 1 (2016): 17-26. [PubMed Link] | [ Full text ]
  • Bondre, I.L.;Holihan, J.L.;Askenasy, E.P.;Greenberg, J.A.;Keith, J.N.;Martindale, R.G.;Roth, J.S.;Liang, M.K.;Ventral Hernia Outcomes, C. "Suture, synthetic, or biologic in contaminated ventral hernia repair." The Journal of surgical research 200, 2 (2016): 488-94. [PubMed Link] | [ Full text ]
  • Johnson, K.C.;Miller, M.T.;Plymale, M.A.;Levy, S.;Davenport, D.L.;Roth, J.S. "Abdominal Wall Reconstruction: A Comparison of Totally Extraperitoneal and Transabdominal Preperitoneal Approaches." Journal of the American College of Surgeons 222, 2 (2016): 159-65. [PubMed Link] | [ Full text ]
  • Levy, S.;Plymale, M.A.;Miller, M.T.;Davenport, D.L.;Roth, J.S. "Laparoscopic parastomal hernia repair: No different than a laparoscopic ventral hernia repair?" Surgical endoscopy 30, 4 (2016): 1542-6. [PubMed Link] | [ Full text ]
  • Bower, C.;Hazey, J.W.;Jones, E.L.;Perry, K.A.;Davenport, D.L.;Roth, J.S. "Laparoscopic Inguinal Hernia Repair With a Novel Hernia Mesh Incorporating a Nitinol Alloy Frame Compared With a Standard Lightweight Polypropylene Mesh." Surgical innovation 22, 5 (2015): 508-13. [PubMed Link] | [ Full text ]
  • Goodenough, C.J.;Liang, M.K.;Nguyen, M.T.;Nguyen, D.H.;Holihan, J.L.;Alawadi, Z.M.;Roth, J.S.;Wray, C.J.;Ko, T.C.;Kao, L.S. "Preoperative Glycosylated Hemoglobin and Postoperative Glucose Together Predict Major Complications after Abdominal Surgery." Journal of the American College of Surgeons 221, 4 (2015): 854-61.e1. [PubMed Link] | [ Full text ]
  • Wennergren, J.E.;Plymale, M.;Davenport, D.;Levy, S.;Hazey, J.;Perry, K.A.;Stigall, K.;Roth, J.S. "Quality-of-life scores in laparoscopic preperitoneal inguinal hernia repair." Surgical endoscopy (2015): [PubMed Link] | [ Full text ]
  • Wennergren, J.E.;Askenasy, E.P.;Greenberg, J.A.;Holihan, J.;Keith, J.;Liang, M.K.;Martindale, R.G.;Trott, S.;Plymale, M.;Roth, J.S. "Laparoscopic ventral hernia repair with primary fascial closure versus bridged repair: a risk-adjusted comparative study." Surgical endoscopy (2015): [PubMed Link] | [ Full text ]
  • Blakeston, A.C.;Alswieleh, A.M.;Heath, G.R.;Roth, J.S.;Bao, P.;Cheng, N.;Armes, S.P.;Leggett, G.J.;Bushby, R.J.;Evans, S.D. "New poly(amino acid methacrylate) brush supports the formation of well-defined lipid membranes." Langmuir : the ACS journal of surfaces and colloids 31, 12 (2015): 3668-77. [PubMed Link] | [ Full text ]
  • Wang, L.;Roth, J.S.;Han, X.;Evans, S.D. "Photosynthetic Proteins in Supported Lipid Bilayers: Towards a Biokleptic Approach for Energy Capture." Small (Weinheim an der Bergstrasse, Germany) 11, 27 (2015): 3306-18. [PubMed Link] | [ Full text ]
  • Liang, M.K.;Goodenough, C.J.;Martindale, R.G.;Roth, J.S.;Kao, L.S. "External validation of the ventral hernia risk score for prediction of surgical site infections." Surgical infections 16, 1 (2015): 36-40. [PubMed Link] | [ Full text ]
  • Ward, N.;Roth, J.S.;Lester, C.C.;Mutiso, L.;Lommel, K.M.;Davenport, D.L. "Anxiolytic medication is an independent risk factor for 30-day morbidity or mortality after surgery." Surgery 158, 2 (2015): 420-7. [PubMed Link] | [ Full text ]
  • Holihan, J.L.;Alawadi, Z.;Martindale, R.G.;Roth, J.S.;Wray, C.J.;Ko, T.C.;Kao, L.S.;Liang, M.K. "Adverse Events after Ventral Hernia Repair: The Vicious Cycle of Complications." Journal of the American College of Surgeons 221, 2 (2015): 478-85. [PubMed Link] | [ Full text ]
  • Roth, J.S.;Brathwaite, C.;Hacker, K.;Fisher, K.;King, J. "Complex ventral hernia repair with a human acellular dermal matrix." Hernia : the journal of hernias and abdominal wall surgery 19, 2 (2015): 247-52. [PubMed Link] | [ Full text ]
  • Goodenough, C.J.;Ko, T.C.;Kao, L.S.;Nguyen, M.T.;Holihan, J.L.;Alawadi, Z.;Nguyen, D.H.;Flores, J.R.;Arita, N.T.;Roth, J.S.;Liang, M.K. "Development and validation of a risk stratification score for ventral incisional hernia after abdominal surgery: hernia expectation rates in intra-abdominal surgery (the HERNIA Project)." Journal of the American College of Surgeons 220, 4 (2015): 405-13. [PubMed Link] | [ Full text ]
  • Woeste, G.;Juratli, M.A.;Habbe, N.;Hannes, S.;El Youzouri, H.;Bechstein, W.O.;Trombetta, F.;Moscato, R.;Ciamporcero, T.;Ghiglione, F.;Morino, M.;Tahir, S.;Baldjiev, T.;Goshev, G.;Pachoov, N.;Eftimov, E.;Kovachevski, S.;Smirnoff, A.;Roth, J.S.;Wennergren, J.;Plymale, M.A.;Zachem, A.;Davenport, D.L.;Mangiante, G.;Passeri, V.;, G.;Kaufmann, R.;Jairam, A.P.;Mulder, I.M.;Wu, Z.;Verhelst, J.;Vennix, S.;Giessen, L.J.;Jeekel, J.;Lange, J.F.;Di Cerbo, F.;Ikhlawi, K.;Baladov, M.;Agha, A.;Iesalnieks, I.;Franklin, M.;Hernandez, M.;Glass, J.;Glover, M.;Gruber-Blum, S.;Fortelny, R.;May, C.;Glaser, K.;Redl, H.;Petter-Puchner, A.;Grossi, J.;Cavazzola, L.T.;Tezza, S.L.;Nery, L.A.;Zortea, J.;Roll, S.;Gorganchian, F.;Santa Maria, V.;Zuvela, M.;Galun, D.;Petrovic, J.;Micev, M.;Palibrk, I.;Bidzic, N.;Colozzi, S.;Clementi, M.;Cianca, G.;Giuliani, A.;Carlei, F.;Schietroma, M.;Amicucci, G.;Hung, M.C.;Cerasani, N.;Meyer, J.;Bulian, D.R.;Heiss, M.M.;Kocaay, A.F.;Eker, T.;Celik, S.U.;Akyol, C.;Cakmak, A. "Topic: Abdominal Wall Hernia - Abdominal wall closure." Hernia : the journal of hernias and abdominal wall surgery 19 Suppl 1, (2015): S198-205. [PubMed Link] | [ Full text ]
  • Levy, S.;Plymale, M.;Davenport, D.L.;Moreno Ponte, O.I.;Roth, J.S. "Patient symptoms correlate poorly with objective measures among patients with gastroesophageal reflux disease." The American surgeon 80, 9 (2014): 901-5. [PubMed Link] | [ Full text ]
  • Dong, Q.;Yan, X.;Kilpatrick, L.E.;Liang, Y.;Mirokhin, Y.A.;Roth, J.S.;Rudnick, P.A.;Stein, S.E. "Tandem mass spectral libraries of peptides in digests of individual proteins: Human Serum Albumin (HSA)." Molecular & cellular proteomics : MCP 13, 9 (2014): 2435-49. [PubMed Link] | [ Full text ]
  • Long, K.L.;Spears, C.;Kenady, D.E.;Roth, J.S. "Implementation of a low-cost laparoscopic skills curriculum in a third-world setting." Journal of surgical education 71, 6 (2014): 860-4. [PubMed Link] | [ Full text ]
  • Taylor, R.W.;Benz, F.;Sigle, D.O.;Bowman, R.W.;Bao, P.;Roth, J.S.;Heath, G.R.;Evans, S.D.;Baumberg, J.J. "Watching individual molecules flex within lipid membranes using SERS." Scientific reports 4, (2014): 5940. [PubMed Link] | [ Full text ]
  • Tharappel, J.C.;Bower, C.E.;Whittington Harris, J.;Ramineni, S.K.;Puleo, D.A.;Roth, J.S. "Doxycycline administration improves fascial interface in hernia repair." The Journal of surgical research 190, 2 (2014): 692-8. [PubMed Link] | [ Full text ]
  • Tharappel, J.C.;Ramineni, S.K.;Reynolds, D.;Puleo, D.A.;Roth, J.S. "Doxycycline impacts hernia repair outcomes." The Journal of surgical research 184, 1 (2013): 699-704. [PubMed Link] | [ Full text ]
  • Roth, J.S.;Buehler, K.C.;Shen, J.;Naughton, M. "Patient factors predict functional outcomes after cruciate retaining TKA: a 2-year follow-up analysis." The Journal of arthroplasty 28, 8 (2013): 1321-6. [PubMed Link] | [ Full text ]
  • Bower, C.;Roth, J.S. "Economics of abdominal wall reconstruction." The Surgical clinics of North America 93, 5 (2013): 1241-53. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Implant wisdom: an endodontist's approach." Dentistry today 32, 7 (2013): 108, 110, 112-3. [PubMed Link] |
  • Reynolds, D.;Davenport, D.L.;Korosec, R.L.;Roth, J.S. "Financial implications of ventral hernia repair: a hospital cost analysis." Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 17, 1 (2013): 159-66; discussion p.166-7. [PubMed Link] | [ Full text ]
  • Orr, N.T.;Davenport, D.L.;Roth, J.S. "Outcomes of simultaneous laparoscopic cholecystectomy and ventral hernia repair compared to that of laparoscopic cholecystectomy alone." Surgical endoscopy 27, 1 (2013): 67-73. [PubMed Link] | [ Full text ]
  • Kohn, G.P.;Price, R.R.;DeMeester, S.R.;Zehetner, J.;Muensterer, O.J.;Awad, Z.;Mittal, S.K.;Richardson, W.S.;Stefanidis, D.;Fanelli, R.D.;SAGES Guidelines, C. "Guidelines for the management of hiatal hernia." Surgical endoscopy 27, 12 (2013): 4409-28. [PubMed Link] | [ Full text ]
  • Auyang, E.D.;Carter, P.;Rauth, T.;Fanelli, R.D.;SAGES Guidelines, C. "SAGES clinical spotlight review: endoluminal treatments for gastroesophageal reflux disease (GERD)." Surgical endoscopy 27, 8 (2013): 2658-72. [PubMed Link] | [ Full text ]
  • Aitchison, S.;Hoopes, C.W.;Roth, J.S. "Venovenous extracorporeal membrane oxygenation for the treatment of acute pulmonary embolism after ventral hernia repair." The American surgeon 79, 4 (2013): 444-6. [PubMed Link] | [ Full text ]
  • Reynolds, D.;Davenport, D.;Roth, J.S. "Predictors of poor outcomes in functionally dependent patients undergoing ventral hernia repair." Surgical endoscopy 27, 4 (2013): 1099-104. [PubMed Link] | [ Full text ]
  • Hanna, E.M.;Voeller, G.R.;Roth, J.S.;Scott, J.R.;Gagne, D.H.;Iannitti, D.A. "Evaluation of ECHO PS Positioning System in a Porcine Model of Simulated Laparoscopic Ventral Hernia Repair." ISRN surgery 2013, (2013): 862549. [PubMed Link] |
  • Todd, H.;Diaz, D.;Roth, J. "Rhabdomyolysis: An unusual complication following endoscopic component separation hernia repair." Journal of surgical case reports 2012, 9 (2012): 18. [PubMed Link] | [ Full text ]
  • Albright, E.L.;Roth, J.S. "Pancreatic lymphangioma." The American surgeon 78, 11 (2012): E476-7. [PubMed Link] | [ Full text ]
  • Albright, E.L.;Roth, J.S. "Recurrent splenic cyst." The American surgeon 78, 11 (2012): E467-8. [PubMed Link] | [ Full text ]
  • Albright, E.L.;Davenport, D.L.;Roth, J.S. "Preoperative functional health status impacts outcomes after ventral hernia repair." The American surgeon 78, 2 (2012): 230-4. [PubMed Link] | [ Full text ]
  • Giurgius, M.;Bendure, L.;Davenport, D.L.;Roth, J.S. "The endoscopic component separation technique for hernia repair results in reduced morbidity compared to the open component separation technique." Hernia : the journal of hernias and abdominal wall surgery 16, 1 (2012): 47-51. [PubMed Link] | [ Full text ]
  • Bao, P.;Cheetham, M.R.;Roth, J.S.;Blakeston, A.C.;Bushby, R.J.;Evans, S.D. "On-chip alternating current electrophoresis in supported lipid bilayer membranes." Analytical chemistry 84, 24 (2012): 10702-7. [PubMed Link] | [ Full text ]
  • Roth, J.S. "CBCT technology: endodontics and beyond, Part 2." Dentistry today 30, 3 (2011): 78, 80-3. [PubMed Link] |
  • Falco, E.E.;Coates, E.E.;Li, E.;Roth, J.S.;Fisher, J.P. "Fabrication and characterization of porous EH scaffolds and EH-PEG bilayers." Journal of biomedical materials research. Part A 97, 3 (2011): 264-71. [PubMed Link] | [ Full text ]
  • Falco, E.E.;Wang, M.O.;Thompson, J.A.;Chetta, J.M.;Yoon, D.M.;Li, E.Z.;Kulkami, M.M.;Shah, S.;Pandit, A.;Roth, J.S.;Fisher, J.P. "Porous EH and EH-PEG scaffolds as gene delivery vehicles to skeletal muscle." Pharmaceutical research 28, 6 (2011): 1306-16. [PubMed Link] | [ Full text ]
  • Diaz, D.F.;Roth, J.S. "Laparoscopic paraesophageal hernia repair with acellular dermal matrix cruroplasty." JSLS : Journal of the Society of Laparoendoscopic Surgeons / Society of Laparoendoscopic Surgeons 15, 3 (2011): 355-60. [PubMed Link] |
  • Albright, E.;Diaz, D.;Davenport, D.;Roth, J.S. "The component separation technique for hernia repair: a comparison of open and endoscopic techniques." The American surgeon 77, 7 (2011): 839-43. [PubMed Link] | [ Full text ]
  • Roth, J.S. "CBCT technology: endodontics and beyond, part I." Dentistry today 30, 2 (2011): 146, 148, 150-1. [PubMed Link] |
  • Roth, J.S.;Dexter, D.D.;Lumpkins, K.;Bochicchio, G.V. "Hydrated vs. freeze-dried human acellular dermal matrix for hernia repair: a comparison in a rabbit model." Hernia : the journal of hernias and abdominal wall surgery 13, 2 (2009): 201-7. [PubMed Link] | [ Full text ]
  • Falco, E.E.;Roth, J.S.;Fisher, J.P. "EH Networks as a scaffold for skeletal muscle regeneration in abdominal wall hernia repair." The Journal of surgical research 149, 1 (2008): 76-83. [PubMed Link] | [ Full text ]
  • Greenberg, R.;Greenwald, B.;Roth, J.S.;Ioffe, O.;Cross, R. "Squamous dysplasia of the rectum in a patient with ulcerative colitis treated with 6-mercaptopurine." Digestive diseases and sciences 53, 3 (2008): 760-4. [PubMed Link] | [ Full text ]
  • Falco, E.E.;Roth, J.S.;Fisher, J.P. "Skeletal muscle tissue engineering approaches to abdominal wall hernia repair." Birth defects research. Part C, Embryo today : reviews 84, 4 (2008): 315-21. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Endodontics versus implants: redefining the paradigm." Dentistry today 27, 4 (2008): 16, 18. [PubMed Link] |
  • Kavic, S.M.;Segan, R.D.;Taylor, M.D.;Roth, J.S. "Laparoscopic management of ventriculoperitoneal and lumboperitoneal shunt complications." JSLS : Journal of the Society of Laparoendoscopic Surgeons / Society of Laparoendoscopic Surgeons 11, 1 (2007): 14-9. [PubMed Link] |
  • Catania, R.A.;Kavic, S.M.;Roth, J.S.;Lee, T.H.;Meyer, T.;Fantry, G.T.;Castellanos, P.F.;Park, A. "Laparoscopic Nissen fundoplication effectively relieves symptoms in patients with laryngopharyngeal reflux." Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 11, 12 (2007): 1579-87; discussion 1587-8. [PubMed Link] | [ Full text ]
  • Milburn, M.L.;Shah, P.K.;Friedman, E.B.;Roth, J.S.;Bochicchio, G.V.;Gorbaty, B.;Silverman, R.P. "Laparoscopically assisted components separation technique for ventral incisional hernia repair." Hernia : the journal of hernias and abdominal wall surgery 11, 2 (2007): 157-61. [PubMed Link] | [ Full text ]
  • Park, A.E.;Roth, J.S.;Kavic, S.M. "Abdominal wall hernia." Current problems in surgery 43, 5 (2006): 326-75. [PubMed Link] | [ Full text ]
  • Park, A.E.;Roth, J.S.;Kavic, S.M. "Abdominal wall hernia. In brief." Current problems in surgery 43, 5 (2006): 322-4. [PubMed Link] | [ Full text ]
  • Kavic, S.M.;Segan, R.D.;George, I.M.;Turner, P.L.;Roth, J.S.;Park, A. "Classification of hiatal hernias using dynamic three-dimensional reconstruction." Surgical innovation 13, 1 (2006): 49-52. [PubMed Link] | [ Full text ]
  • Jenkins, N.L.;Roth, J.S.;Johnson, J.O.;Pofahl, W.E. "Laparoscopic colorectal surgery: indications and techniques." Current surgery 62, 3 (2005): 319-23. [PubMed Link] | [ Full text ]
  • Xu, M.;Geer, L.Y.;Bryant, S.H.;Roth, J.S.;Kowalak, J.A.;Maynard, D.M.;Markey, S.P. "Assessing data quality of peptide mass spectra obtained by quadrupole ion trap mass spectrometry." Journal of proteome research 4, 2 (2005): 300-5. [PubMed Link] | [ Full text ]
  • McKinlay, R.;Sanfiel, F.;Roth, J.S. "The current role of laparoscopy in staging upper gastrointestinal malignancies." Current surgery 62, 1 (2005): 35-7. [PubMed Link] | [ Full text ]
  • Whetsone, D.;Hazey, J.;Pofahl WE, 2nd;Roth, J.S. "Current management of diverticulitis." Current surgery 61, 4 (2004): 361-5. [PubMed Link] | [ Full text ]
  • Roth, J.S.;Johnson, J.;Hazey, J.;Pofahl, W. "Current laparoscopic inguinal hernia repair." Current surgery 61, 1 (2004): 53-6. [PubMed Link] | [ Full text ]
  • Johnson, J.;Roth, J.S.;Hazey, J.W.;Pofahl, W.E. "The history of open inguinal hernia repair." Current surgery 61, 1 (2004): 49-52. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Endodontic hybridization. Access and answers." Dentistry today 23, 4 (2004): 94-6. [PubMed Link] |
  • Bower, C.E.;Reade, C.C.;Kirby, L.W.;Roth, J.S. "Complications of laparoscopic incisional-ventral hernia repair: the experience of a single institution." Surgical endoscopy 18, 4 (2004): 672-5. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Minimally invasive approaches to pancreatic pseudocysts." Current surgery 60, 6 (2003): 591-2. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Peanut allergy." The New England journal of medicine 349, 3 (2003): 301-3; author reply 301-3. [PubMed Link] |
  • Roth, J.S. "Residency reform." Current surgery 59, 5 (2002): 431-2. [PubMed Link] | [ Full text ]
  • Roth, J.S.;Newman, E.C. "Gluteal compartment syndrome and sciatica after bone marrow biopsy: a case report and review of the literature." The American surgeon 68, 9 (2002): 791-4. [PubMed Link] |
  • Zhang, H.;Ford H, J.;Roth, J.S.;Kelley, J.A. "Evaluation of a fluorogenic derivatization method for the reversed-phase HPLC analysis of 2'-beta-fluoro-2',3'-dideoxyadenosine, a new anti-AIDS drug." Journal of pharmaceutical and biomedical analysis 25, 2 (2001): 285-97. [PubMed Link] | [ Full text ]
  • Park, A.;Schwartz, R.W.;Witzke, D.B.;Roth, J.S.;Mastrangelo, M.;Birch, D.W.;Jennings, C.D.;Lee, E.Y.;Hoskins, J. "A pilot study of new approaches to teaching anatomy and pathology." Surgical endoscopy 15, 3 (2001): 245-50. [PubMed Link] | [ Full text ]
  • Roth, J.S.;Park, A.E. "Laparoscopic pancreatic cystgastrostomy: the lesser sac technique." Surgical laparoscopy, endoscopy & percutaneous techniques 11, 3 (2001): 201-3. [PubMed Link] |
  • Roth, J.S.;Wang, J.;Kelley, J.A. "Determination of lodenosine and its major metabolite in human plasma by liquid chromatography/electrospray ionization tandem mass spectrometry." Journal of mass spectrometry : JMS 35, 11 (2000): 1313-9. [PubMed Link] |
  • Roth, J.S.;Park, A.E.;Gewirtz, R. "Minilaparoscopically assisted placement of ventriculoperitoneal shunts." Surgical endoscopy 14, 5 (2000): 461-3. [PubMed Link] |
  • Roth, J.S.;McCully, C.M.;Balis, F.M.;Poplack, D.G.;Kelley, J.A. "2'-beta-fluoro-2',3'-dideoxyadenosine, lodenosine, in rhesus monkeys: plasma and cerebrospinal fluid pharmacokinetics and urinary disposition." Drug metabolism and disposition: the biological fate of chemicals 27, 10 (1999): 1128-32. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Endodontics in the new millennium. Interview with Dr. Jack S. Roth. Interview by Phillip Bonner." Dentistry today 18, 5 (1999): 72-7. [PubMed Link] |
  • Roth, J.S. "Reconstructive endodontics." Dentistry today 17, 1 (1998): 64-7. [PubMed Link] |
  • Roth, J.S.;Ford H, J.;Tanaka, M.;Mitsuya, H.;Kelley, J.A. "Determination of 2'-beta-fluoro-2',3'-dideoxyadenosine, an experimental anti-AIDS drug, in human plasma by high-performance liquid chromatography." Journal of chromatography. B, Biomedical sciences and applications 712, 1-2 (1998): 199-210. [PubMed Link] |
  • Driscoll, J.S.;Siddiqui, M.A.;Ford H, J.;Kelley, J.A.;Roth, J.S.;Mitsuya, H.;Tanaka, M.;Marquez, V.E. "Lipophilic, acid-stable, adenosine deaminase-activated anti-HIV prodrugs for central nervous system delivery. 3. 6-Amino prodrugs of 2'-beta-fluoro-2',3'-dideoxyinosine." Journal of medicinal chemistry 39, 8 (1996): 1619-25. [PubMed Link] | [ Full text ]
  • Donzanti, B.A.;Kelley, J.A.;Tomaszewski, J.E.;Roth, J.S.;Tosca, P.;Placke, M.;Singer, A.;Yarrington, J.T.;Driscoll, J.S. "Acute cardiotoxicity of the Anti-HIV dideoxynucleoside, F-ddA, in the rat." Fundamental and applied toxicology : official journal of the Society of Toxicology 27, 2 (1995): 167-76. [PubMed Link] |
  • Roth, J.S.;Walczyk, J.S. "Occult tooth fragments spontaneously extruded after six months." Cutis 54, 4 (1994): 253-4. [PubMed Link] |
  • Roth, J.S.;Grossman, M.E. "Images in clinical medicine. Cutaneous lesions of disseminated candidiasis." The New England journal of medicine 330, 23 (1994): 1650. [PubMed Link] | [ Full text ]
  • Roth, J.S.;Kelley, J.A.;Chun, H.G.;Ward, F.T. "Simultaneous measurement of the cell-differentiating agent hexamethylene bisacetamide and its metabolites by gas chromatography." Journal of chromatography 652, 2 (1994): 149-59. [PubMed Link] |
  • Greenbaum, R.S.;Roth, J.S.;Grossman, M.E. "Subcutaneous nodule in a cardiac transplant. Cutaneous aspergillosis." Archives of dermatology 129, 9 (1993): 1191, 1194. [PubMed Link] | [ Full text ]
  • Roth, J.S.;Grossman, M.E. "Linear Kaposi's sarcoma in HIV disease." Journal of the American Academy of Dermatology 29, 3 (1993): 488. [PubMed Link] |
  • Roth, J.S.;Rabinowitz, A.D.;Benson, M.;Grossman, M.E. "Bilateral renal cell carcinoma in the Birt-Hogg-Dubé syndrome." Journal of the American Academy of Dermatology 29, 6 (1993): 1055-6. [PubMed Link] |
  • Mautner, G.;Roth, J.S.;Grossman, M.E. "Leukocytoclastic vasculitis in association with cryoglobulinemia and renal cell carcinoma." Nephron 63, 3 (1993): 356-7. [PubMed Link] |
  • Siddiqui, M.A.;Driscoll, J.S.;Marquez, V.E.;Roth, J.S.;Shirasaka, T.;Mitsuya, H.;Barchi JJ, J.;Kelley, J.A. "Chemistry and anti-HIV properties of 2'-fluoro-2',3'-dideoxyarabinofuranosylpyrimidines." Journal of medicinal chemistry 35, 12 (1992): 2195-201. [PubMed Link] |
  • Ward, F.T.;Kelley, J.A.;Roth, J.S.;Lombardo, F.A.;Weiss, R.B.;Leyland-Jones, B.;Chun, H.G. "Phase I bioavailability and pharmacokinetic study of hexamethylene bisacetamide (NSC 95580) administered via nasogastric tube." Cancer research 51, 7 (1991): 1803-10. [PubMed Link] | [ Full text ]
  • Roth, J.S.;Hsieh, L.L.;Peraino, C.;Weinstein, I.B. "Isolation of a complementary DNA encoding the catalytic subunit of protein kinase A and studies on the expression of this sequence in rat hepatomas and regenerating liver." Cancer research 50, 6 (1990): 1675-80. [PubMed Link] | [ Full text ]
  • Marquez, V.E.;Tseng, C.K.;Mitsuya, H.;Aoki, S.;Kelley, J.A.;Ford H, J.;Roth, J.S.;Broder, S.;Johns, D.G.;Driscoll, J.S. "Acid-stable 2'-fluoro purine dideoxynucleosides as active agents against HIV." Journal of medicinal chemistry 33, 3 (1990): 978-85. [PubMed Link] |
  • Collins, J.M.;Klecker RW, J.;Kelley, J.A.;Roth, J.S.;McCully, C.L.;Balis, F.M.;Poplack, D.G. "Pyrimidine dideoxyribonucleosides: selectivity of penetration into cerebrospinal fluid." The Journal of pharmacology and experimental therapeutics 245, 2 (1988): 466-70. [PubMed Link] | [ Full text ]
  • Heideman, R.L.;Kelley, J.A.;Packer, R.J.;Reaman, G.H.;Roth, J.S.;Balis, F.;Ettinger, L.J.;Doherty, K.M.;Jeffries, S.L.;Poplack, D.G. "A pediatric phase I and pharmacokinetic study of spirohydantoin mustard." Cancer research 48, 8 (1988): 2292-5. [PubMed Link] | [ Full text ]
  • Kelley, J.A.;Litterst, C.L.;Roth, J.S.;Vistica, D.T.;Poplack, D.G.;Cooney, D.A.;Nadkarni, M.;Balis, F.M.;Broder, S.;Johns, D.G. "The disposition and metabolism of 2',3'-dideoxycytidine, an in vitro inhibitor of human T-lymphotrophic virus type III infectivity, in mice and monkeys." Drug metabolism and disposition: the biological fate of chemicals 15, 5 (1987): 595-601. [PubMed Link] | [ Full text ]
  • Marquez, V.E.;Tseng, C.K.;Kelley, J.A.;Mitsuya, H.;Broder, S.;Roth, J.S.;Driscoll, J.S. "2',3'-Dideoxy-2'-fluoro-ara-A. An acid-stable purine nucleoside active against human immunodeficiency virus (HIV)." Biochemical pharmacology 36, 17 (1987): 2719-22. [PubMed Link] | [ Full text ]
  • Kelley, J.A.;Driscoll, J.S.;McCormack, J.J.;Roth, J.S.;Marquez, V.E. "Furanose-pyranose isomerization of reduced pyrimidine and cyclic urea ribosides." Journal of medicinal chemistry 29, 11 (1986): 2351-8. [PubMed Link] |
  • Haces, A.;Driscoll, J.S.;Roth, J.S.;Heideman, R.L.;Kelley, J.A. "Spiromustine analogues. Relationships between structure, plasma stability, and antitumor activity." Journal of pharmaceutical sciences 75, 3 (1986): 313-6. [PubMed Link] | [ Full text ]
  • Eshghi, A.M.;Roth, J.S.;Smith, A.D. "Percutaneous transperitoneal approach to a pelvic kidney for endourological removal of staghorn calculus." The Journal of urology 134, 3 (1985): 525-7. [PubMed Link] |
  • Curt, G.A.;Kelley, J.A.;Fine, R.L.;Huguenin, P.N.;Roth, J.S.;Batist, G.;Jenkins, J.;Collins, J.M. "A phase I and pharmacokinetic study of dihydro-5-azacytidine (NSC 264880)." Cancer research 45, 7 (1985): 3359-63. [PubMed Link] | [ Full text ]
  • Litterst, C.L.;Roth, J.S.;Kelley, J.A. "Distribution, elimination, metabolism and bioavailability of hexamethylenebisacetamide in rats." Investigational new drugs 3, 3 (1985): 263-72. [PubMed Link] |
  • Malicka-Blaszkiewicz, M.;Roth, J.S. "Evidence for the presence of DNase-actin complex in L1210 leukemia cells." FEBS letters 153, 1 (1983): 235-9. [PubMed Link] | [ Full text ]
  • Malicka-Blaszkiewicz, M.;Roth, J.S. "Some factors affecting the interaction between actin in leukemic L1210 cells and DNASE I." Biochemical and biophysical research communications 102, 2 (1981): 594-601. [PubMed Link] | [ Full text ]
  • Blocker, R.;Roth, J.S. "The reduction of uridine 5'-diphosphate and uridine 5'-triphosphate in some transplantable rat hepatomas." Cancer research 37, 6 (1977): 1923-8. [PubMed Link] | [ Full text ]
  • Blocker, R.;Roth, J.S. "Factors affecting deoxycytidylate deaminase activity in some transplantable rat hepatomas." Cancer research 37, 6 (1977): 1918-22. [PubMed Link] | [ Full text ]
  • Dickens, M.S.;Lucas-Lenard, J.;Roth, J.S. "Evidence for preformed mRNA in the induction of TMP synthetase in Tetrahymena pyriformis." Experimental cell research 110, 2 (1977): 331-5. [PubMed Link] | [ Full text ]
  • Roth, J.J.;Roth, J.S. "Thymidylate synthetase activity in the Novikoff hepatoma." Cancer research 36, 12 (1976): 4500-3. [PubMed Link] | [ Full text ]
  • Dickens, M.S.;Lucas-Leonard, J.;Roth, J.S. "Induction of thymidylate synthetase activity in Tetrahymena by cyclic guanosine monophosphate." Biochemical and biophysical research communications 67, 4 (1975): 1319-25. [PubMed Link] |
  • Zan-Kowalczewska, M.;Roth, J.S. "On the similarity between ribonuclease inhibitor and beta-estradiol receptor protein." Biochemical and biophysical research communications 65, 3 (1975): 833-7. [PubMed Link] | [ Full text ]
  • Losty, T.;Roth, J.S.;Shults, G. "Effect of irradiation and heating on proteolytic activity of meat samples." Journal of agricultural and food chemistry 21, 2 (1973): 275-7. [PubMed Link] |
  • Roth, J.S.;Juster, H. "On the absence of ribonuclease inhibitor in rat liver nuclei." Biochimica et biophysica acta 287, 3 (1972): 474-6. [PubMed Link] |
  • Artman, M.;Roth, J.S. "Chromosomal RNA: an artifact of preparation?" Journal of molecular biology 60, 2 (1971): 291-301. [PubMed Link] | [ Full text ]
  • Atkinson, B.G.;Roth, J.S. "Control of the synthesis of DNA precursors during Rana pipiens development." Biochimica et biophysica acta 240, 1 (1971): 12-22. [PubMed Link] |
  • Roth, J.S.;Losty, T.;Wierbicki, E. "Assay of proteolytic enzyme activity using a 14C-labeled hemoglobin." Analytical biochemistry 42, 1 (1971): 214-21. [PubMed Link] | [ Full text ]
  • Buccino RJ, J.;Roth, J.S. "Partial purification and properties of ATP:GMP phosphransferase from rat liver." Archives of biochemistry and biophysics 132, 1 (1969): 49-61. [PubMed Link] |
  • Dods, R.F.;Roth, J.S. "Halogenation of nucleosides by (halomethylene) dimethylene ammonium halides." Tetrahedron letters 3 (1969): 165-8. [PubMed Link] |
  • Gold, L.M.;Roth, J.S. "Preparation of a deoxynucleoprotein fraction with high priming activity from chick embryonic tissue by use of sodium deoxycholate." Archives of biochemistry and biophysics 126, 3 (1968): 922-32. [PubMed Link] |
  • Roth, J.S. "RNA competition in RNA-DNA hybridization systems." Science (New York, N.Y.) 162, 3854 (1968): 699. [PubMed Link] | [ Full text ]
  • Roth, J.S.;Hultin, T. "Extraction of ribosomal proteins by displacement with protamine." FEBS letters 1, 1 (1968): 16-20. [PubMed Link] | [ Full text ]
  • Scholl, A.;Herrmann, H.;Roth, J.S. "Studies of muscle development. 3. An evaluation of thymidylate kinase activity with respect to cell proliferation in developing chick leg muscle." Life sciences 7, 2 (1968): 91-7. [PubMed Link] |
  • Norton, J.;Roth, J.S. "Some aspects of nuclease activity in Anacystis nidulans and other algae." Comparative biochemistry and physiology 23, 2 (1967): 361-71. [PubMed Link] |
  • Wagner, R.L.;Roth, J.S. "Some properties of beta-glucuronidase activity in normal rat liver and in several transplantable rat hepatomas." Cancer research 27, 11 (1967): 2053-9. [PubMed Link] | [ Full text ]
  • Norton, J.;Roth, J.S. "A ribonuclease specific for 2'-O-methylated ribonucleic acid." The Journal of biological chemistry 242, 9 (1967): 2029-34. [PubMed Link] | [ Full text ]
  • Ambellan, E.;Roth, J.S. "Steroid effects on rat thymus acid ribonuclease." Biochemical and biophysical research communications 28, 2 (1967): 244-8. [PubMed Link] | [ Full text ]
  • Roth, J.S.;Hurley, D. "The reaction of ribonuclease inhibitor with modified ribonucleases." The Biochemical journal 101, 1 (1966): 112-9. [PubMed Link] |
  • Utsunomiya, T.;Roth, J.S. "Studies on the function of intracellular ribonucleases. V. Ribonuclease activity in ribosomes and polysomes prepared from rat liver and hepatomas." The Journal of cell biology 29, 3 (1966): 395-403. [PubMed Link] | [ Full text ]
  • Utsunomiya, T.;Roth, J.S. "Studies on the function of intracellular ribonucleases. IV. Some observations on the properties of ribosomes and polysomes from rat liver and hepatomas." The Journal of cell biology 29, 3 (1966): 387-93. [PubMed Link] | [ Full text ]
  • Eley, J.;Roth, J.S. "The specificity of a nuclease from chicken pancreas." The Journal of biological chemistry 241, 13 (1966): 3070-7. [PubMed Link] | [ Full text ]
  • Eley, J.;Roth, J.S. "Partial purification and properties of a nuclease from chicken pancreas." The Journal of biological chemistry 241, 13 (1966): 3063-9. [PubMed Link] | [ Full text ]
  • NAGYVARY, J.;Roth, J.S. "STUDIES ON THE SYNTHESIS OF THE NATURAL INTERNUCLEOTIDE BOND BY THE USE OF CYCLONUCLEOSIDES." Tetrahedron letters 11, (1965): 617-20. [PubMed Link] |
  • SHEID, B.;Morris, H.P.;Roth, J.S. "DISTRIBUTION AND ACTIVITY OF ASPARTATE AMINOTRANSFERASE IN SOME RAPIDLY PROLIFERATING TISSUES." The Journal of biological chemistry 240, (1965): 3016-22. [PubMed Link] | [ Full text ]
  • Wojnar, R.J.;Roth, J.S. "Ribonuclease inhibitor and latent ribonuclease in rat liver during feeding of 2-acetamidofluorene." Cancer research 25, 11 (1965): 1913-8. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Histones in development, growth and cancer." Nature 207, 997 (1965): 599-601. [PubMed Link] |
  • Roth, J.S.;Buccino, G. "Biochemical studies on irradiated protozoa. 3. Catalase activity in Tetrahymena pyriformis W." The Journal of protozoology 12, 3 (1965): 432-8. [PubMed Link] |
  • BUKOVSKY, J.;Roth, J.S. "SOME FACTORS AFFECTING THE PHOSPHORYLATION OF THYMIDINE BY TRANSPLANTABLE RAT HEPATOMAS." Cancer research 25, (1965): 358-64. [PubMed Link] | [ Full text ]
  • Roth, J.S. "INCREASED STABILITY OF TEMPLATES FOR SOME ENZYMES OF DNA SYNTHESIS IN TUMORS: DEOXYCYTIDYLATE DEAMINASE, THYMIDINE AND THYMIDYLATE KINASE." Life sciences 3, (1964): 1145-9. [PubMed Link] |
  • Wojnar, R.J.;Roth, J.S. "METAL IONS IN RIBONUCLEIC ACID: THEIR NATURE AND INTERFERENCE WITH THE ASSAY FOR RIBONUCLEASE AND RIBONUCLEASE INHIBITOR." Biochimica et biophysica acta 87, (1964): 17-27. [PubMed Link] |
  • WHITCUTT, J.M.;Roth, J.S. "RIBONUCLEIC ACID SYNTHESIS AND TURNOVER IN RAT LIVER AND IN A RAPIDLY GROWING TRANSPLANTABLE HEPATOMA." Biochimica et biophysica acta 87, (1964): 380-7. [PubMed Link] |
  • ZALITE, B.R.;Roth, J.S. "AN ASSAY FOR AND SOME PROPERTIES OF DEOXYRIBONUCLEASE INHIBITOR IN RAT LIVER." Archives of biochemistry and biophysics 107, (1964): 16-22. [PubMed Link] |
  • Roth, J.S.;HILTON, S.;Morris, H.P. "RIBONUCLEASE ACTIVITY IN SOME TRANSPLANTABLE RAT HEPATOMAS." Cancer research 24, (1964): 294-301. [PubMed Link] | [ Full text ]
  • Roth, J.S.;Wagner, M.;KOTHS, M. "THE EFFECT OF WHOLE BODY GAMMA IRRADIATION ON THE DEOXYCYTIDYLATE, DEOXYADENOSINE, AND DEOXYGUANOSINE DEAMINASE ACTIVITY OF RAT SPLEEN AND THYMUS." Radiation research 22, (1964): 722-9. [PubMed Link] |
  • Roth, J.S. "BIOLOGICAL INFORMATION IN A SINGLE STRAND OF DEOXYRIBONUCLEIC ACID." Nature 202, (1964): 182-3. [PubMed Link] |
  • BUKOVSKY, J.;Roth, J.S. "Studies on thymidylate phosphatase, thymidine kinase and thymidylate kinase activities in some transplantable rat hepatomas." Advances in enzyme regulation 2, (1964): 371-82. [PubMed Link] | [ Full text ]
  • Roth, J.S.;HILTON, S. "The effect of whole-body x-irradiation on the distribution of acid deoxyribonuclease and beta-galactosidase in subcellular fractions of rat spleen." Radiation research 19, (1963): 42-9. [PubMed Link] |
  • Roth, J.S.;SHEID, B.;Morris, H.P. "Some observations on the deamination of deoxynucleotides and deoxynucleosides by normal rat liver and hepatomas." Cancer research 23, (1963): 454-61. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Ribonuclease activity and cancer: a review." Cancer research 23, (1963): 657-66. [PubMed Link] | [ Full text ]
  • Roth, J.S.;Buccino, G. "Some aspects of deoxynucleotide metabolism in the developing chick embryo." Archives of biochemistry and biophysics 101, (1963): 516-22. [PubMed Link] |
  • Roth, J.S. "A hypothesis concerning patterns of deoxynucleotide metabolism in tumors in relation to rate of cell proliferation." Journal of theoretical biology 4, 1 (1963): 113-23. [PubMed Link] | [ Full text ]
  • Roth, J.S.;Buccino, G.;KLEIN, N.W. "INHIBITION OF GROWTH OF CHICK EMBRYO BY INHIBITION OF DEOXYCYTIDYLATE DEAMINASE." Science (New York, N.Y.) 142, 3598 (1963): 1473-4. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Biochemical studies on irradiated protozoa, L. Effect of metabolites on the respiration of x-irradiated Tetrahymena pyriformis." The Journal of protozoology 9, (1962): 142-6. [PubMed Link] |
  • Roth, J.S.;BUKOVSKY, J.;EICHEL, H.J. "The effect of whole-body x-irradiation on the activity of some acid hydrolases in homogenates and subcellular fractions of rat spleen." Radiation research 16, (1962): 27-36. [PubMed Link] |
  • EICHEL, H.J.;Roth, J.S. "Intracellular localization of enzymes in spleen. II. Some properties and the distribution of ribonuclease in rat spleen." The Journal of cell biology 12, (1962): 263-76. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Ribonuclease. IX. Further studies on ribonuclease inhibitor." Biochimica et biophysica acta 61, (1962): 903-15. [PubMed Link] |
  • Roth, J.S.;WOJNAR, R. "An impurity in RNA preparations that interferes with assays for ribonuclease and ribonuclease inhibitor." Biochemical and biophysical research communications 6, (1961): 151-4. [PubMed Link] |
  • Roth, J.S.;BUKOVSKY, J. "Studies on an N-demethylating system in rat liver microsomes." The Journal of pharmacology and experimental therapeutics 131, (1961): 275-81. [PubMed Link] | [ Full text ]
  • EICHEL, H.J.;Roth, J.S. "Some theoretical considerations of changes in tissue enzyme activity after whole-body x-irradiation of animals." Radiation research 12, (1960): 258-65. [PubMed Link] |
  • Roth, J.S. "Studies on the function of intracellular ribonucleases. II. The interaction of ribonucleprotein and enzymes." The Journal of biophysical and biochemical cytology 7, (1960): 443-53. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Studies on the function of intracellular ribonucleases. III. The relationship of the ribonuclease activity of rat liver microsomes to their biological activity." The Journal of biophysical and biochemical cytology 8, (1960): 665-73. [PubMed Link] |
  • EDMONDS, M.;Roth, J.S. "The purification and properties of a ribonuclease from squid." Archives of biochemistry and biophysics 89, (1960): 207-12. [PubMed Link] |
  • Roth, J.S. "Comparative studies ontissue ribonucleases." Annals of the New York Academy of Sciences 81, (1959): 611-7. [PubMed Link] | [ Full text ]
  • Roth, J.S.;EICHEL, H.J. "The effect of total-body x-irradiation on the distribution of ribonuclease activity in subcellular fractions of rat spleen." Radiation research 11, (1959): 572-81. [PubMed Link] |
  • Roth, J.S. "Observations on the instability in the ribonucleic acid of microsomal ribonucleoprotein." Archives of biochemistry and biophysics 74, 1 (1958): 277-9. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Radiation Hazards." Science (New York, N.Y.) 128, 3337 (1958): 1532-4. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Ribonuclease. VIII. Studies on the inactive ribonuclease in the supernatant fraction of rat liver." The Journal of biological chemistry 231, 2 (1958): 1097-105. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Ribonuclease. VII. Partial purification and characterization of a ribonuclease inhibitor in rat liver supernatant fraction." The Journal of biological chemistry 231, 2 (1958): 1085-95. [PubMed Link] | [ Full text ]
  • Roth, J.S. "The effect of feeding 2-acetylaminofluorene on ribonuclease activity in the serum and liver mitochondria of rats." Cancer research 17, 10 (1957): 991-4. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Ribonuclease. VI. Partial purification and characterization of the ribonucleases of rat liver mitochondria." The Journal of biological chemistry 227, 2 (1957): 591-604. [PubMed Link] | [ Full text ]
  • Roth, J.S.;MILSTEIN, S.W. "Some effects of excess methionine on lipide metabolism in the rat." Archives of biochemistry and biophysics 70, 2 (1957): 392-400. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Ribonuclease. V. Studies on the properties and distribution of ribonuclease inhibitor in the rat." Biochimica et biophysica acta 21, 1 (1956): 34-43. [PubMed Link] |
  • Roth, J.S. "Ribonuclease. IV. The effect of whole body x-irradiation on the ribonuclease system of rat liver." Archives of biochemistry and biophysics 60, 1 (1956): 7-13. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Studies on the function of intracellular ribonucleases. I. The action of cobalt and nickel on Tetrahymena pyriformis W." Experimental cell research 10, 1 (1956): 146-54. [PubMed Link] | [ Full text ]
  • Roth, J.S. "The metabolism of methionine sulfoximine." Archives of biochemistry and biophysics 52, 1 (1954): 269-71. [PubMed Link] |
  • Roth, J.S. "Ribonuclease. III. Ribonuclease activity in rat liver and kidney." The Journal of biological chemistry 208, 1 (1954): 181-94. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Incorporation of N15 into protein and P32 into nucleic acid of the thermally injured rat." The American journal of physiology 176, 3 (1954): 471-4. [PubMed Link] |
  • Roth, J.S. "Certain effects of 2-aminofluorene and alpha- and beta-naphthylamines on Tetrahymena pyriformis." Cancer research 14, 5 (1954): 346-51. [PubMed Link] | [ Full text ]
  • Roth, J.S. "A possible function of intracellular ribonucleases." Nature 174, 4420 (1954): 129. [PubMed Link] |
  • Roth, J.S.;EICHEL, H.J.;GINTER, E. "The oxidation of amino acids by Tetrahymena pyriformis W." Archives of biochemistry and biophysics 48, 1 (1954): 112-9. [PubMed Link] | [ Full text ]
  • Roth, J.S.;EICHEL, H.J.;WASE, A.;ALPER, C.;BOYD, M.J. "Effect of total body x-irradiation on some enzymes of rat tissues." Archives of biochemistry and biophysics 44, 1 (1953): 95-101. [PubMed Link] | [ Full text ]
  • Roth, J.S. "Ribonuclease. II. Activators and inhibitors for ribonuclease." Archives of biochemistry and biophysics 44, 2 (1953): 265-70. [PubMed Link] |
  • Roth, J.S. "Effect of sulphydryl reactants on liver ribonuclease." Nature 171, 4342 (1953): 127-8. [PubMed Link] |
  • Roth, J.S.;WASE, A.;EICHEL, H.J. "Studies with methionine sulfoximine." The Journal of biological chemistry 200, 2 (1953): 647-56. [PubMed Link] | [ Full text ]
  • PAFF, G.H.;SUGIURA, H.T.;BOCHER, C.A.;Roth, J.S. "The probable mechanism of heparin inhibition of mitosis." The Anatomical record 114, 3 (1952): 499-505. [PubMed Link] |
  • Roth, J.S.;MILSTEIN, S.W. "Ribonuclease. I. A new assay method with P32 labeled yeast ribonucleic acid." The Journal of biological chemistry 196, 2 (1952): 489-98. [PubMed Link] | [ Full text ]
  • Roth, J.S.;WASE, A.;REINER, L. "The distribution of S35-labeled L-methionine sulfoximine in the rat." Science (New York, N.Y.) 115, 2983 (1952): 236-8. [PubMed Link] | [ Full text ]
  • Roth, J.S.;ALLISON, J.B.;MILCH, L.J. "The sulfur balance of rats fed excess DL-methionine plus glycine or DL-alanine." The Journal of biological chemistry 186, 1 (1950): 113-8. [PubMed Link] | [ Full text ]
  • GREEN, J.W.;Roth, J.S. "The effect of p32 on the division time of Arbacia eggs." The Biological bulletin 99, 2 (1950): 358. [PubMed Link] |
  • Roth, J.S.;ELLIOTT, A.M.;Hunter, R.L. "Some observations on phosphate uptake by Tetrahymena geleii." The Biological bulletin 99, 2 (1950): 335-6. [PubMed Link] |
  • Roth, J.S.;ALLISON, J.B. "The effect of feeding excess glycine, L-arginine, and DL-methionine to rats on a casein diet." Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 70, 2 (1949): 327-30. [PubMed Link] |