Mary B Sheppard, M.D.

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Publications

741 S. Limestone St., BBSRB 247, Lexington, KY 40536-0509

Position(s):

Assistant Professor, Family Medicine and Surgery

Affiliation(s):

Family and Community Medicine

Cardiovascular Research Center

Other Affiliation(s):

CVRC - Core Faculty

Family and Community Medicine

Surgery/Department

Interests / Specialties:

Genetics

Bio / Education:

BS, Biochemistry and Molecular Biology, Centre College 2004-2008
MD, University of Kentucky College of Medicine 2008-2012
Family Medicine Residency, University of Virginia 2012-2015

Selected Publications:

-FBN1 isoform expression varies in a tissue and development-specific fashion. M. Burchett, I. Ling, S. Estus. Biochemical and Biophysical Research Communications 411 (2011) pp. 323-328.

PubMed Publications:

Chen, JZ ; Sawada, H.; Moorleghen, JJ ; Weiland, M.; Daugherty, A.; Sheppard, MB "Aortic Strain Correlates with Elastin Fragmentation in Fibrillin-1 Hypomorphic Mice." Circulation reports 1, 5 (2019): 199-205. [PubMed Link] |
Sawada, H.; Chen, JZ ; Wright, BC ; Sheppard, MB ; Lu, HS ; Daugherty, A. "Heterogeneity of Aortic Smooth Muscle Cells: A Determinant for Regional Characteristics of Thoracic Aortic Aneurysms?" Journal of translational internal medicine 6, 3 (2018): 93-96. [PubMed Link] |
Sheppard, MB "Researcher, Heal Thyself?" Circulation research 121, 10 (2017): 1122-1123. [PubMed Link] | [ Full text ]
Daugherty, A.; Chen, Z.; Sawada, H.; Rateri, DL ; Sheppard, MB "Transforming Growth Factor-β in Thoracic Aortic Aneurysms: Good, Bad, or Irrelevant?" Journal of the American Heart Association 6, 1 (2017): [PubMed Link] | [ Full text ]
Lu, H.; Sheppard, M.; Daugherty, A. "Calcification in atherosclerotic lesions." Current opinion in lipidology 27, 5 (2016): 543-4. [PubMed Link] | [ Full text ]
Sheppard, M.; Rateri, DL ; Daugherty, A. "miRs, miRs in the Wall, Who Is the Most Causative of Them All?" Journal of the American College of Cardiology 67, 25 (2016): 2978-80. [PubMed Link] | [ Full text ]
Sheppard, MB ; Daugherty, A.; Lu, H. "Insights into ascending aortic aneurysm pathogenesis using in vivo and ex vivo imaging systems in angiotensin II-infused mice." Journal of thoracic disease 8, 8 (2016): E822-4. [PubMed Link] | [ Full text ]