Piotr Rychahou, MD

Bio / Education: 

Medical School
Byelorussian State Medical University, Minsk, Belarus, Cum Laude

Graduate School (MMS)
University of Texas Medical Branch, Galveston, TX

Research Interests
To elucidate the role of PI3K/Akt pathway components in colorectal carcinoma oncogenesis

PubMed Publications: 

  • Wydra, R.J.;Rychahou, P.G.;Evers, B.M.;Anderson, K.W.;Dziubla, T.D.;Hilt, J.Z. "The role of ROS generation from magnetic nanoparticles in an alternating magnetic field on cytotoxicity." Acta biomaterialia 25, (2015): 284-90. [PubMed Link] | [ Full text ]
  • Li, H.;Rychahou, P.G.;Cui, Z.;Pi, F.;Evers, B.M.;Shu, D.;Guo, P.;Luo, W. "RNA Nanoparticles Derived from Three-Way Junction of Phi29 Motor pRNA Are Resistant to I-125 and Cs-131 Radiation." Nucleic acid therapeutics 25, 4 (2015): 188-97. [PubMed Link] |
  • Xiong, G.;Deng, L.;Zhu, J.;Rychahou, P.G.;Xu, R. "Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition." BMC cancer 14, (2014): 1. [PubMed Link] | [ Full text ]
  • Wang, S.;Haque, F.;Rychahou, P.G.;Evers, B.M.;Guo, P. "Engineered nanopore of Phi29 DNA-packaging motor for real-time detection of single colon cancer specific antibody in serum." ACS nano 7, 11 (2013): 9814-22. [PubMed Link] | [ Full text ]
  • Kim, J.T.;Li, J.;Jang, E.R.;Gulhati, P.;Rychahou, P.G.;Napier, D.L.;Wang, C.;Weiss, H.L.;Lee, E.Y.;Anthony, L.;Townsend CM, J.;Liu, C.;Evers, B.M. "Deregulation of Wnt/β-catenin signaling through genetic or epigenetic alterations in human neuroendocrine tumors." Carcinogenesis 34, 5 (2013): 953-61. [PubMed Link] | [ Full text ]
  • Dong, C.;Wu, Y.;Wang, Y.;Wang, C.;Kang, T.;Rychahou, P.G.;Chi, Y.I.;Evers, B.M.;Zhou, B.P. "Interaction with Suv39H1 is critical for Snail-mediated E-cadherin repression in breast cancer." Oncogene 32, 11 (2013): 1351-62. [PubMed Link] | [ Full text ]
  • Valentino, J.D.;Rychahou, P.G.;Mustain, W.C.;Elliott, V.A.;Evers, B.M. "Murine portal vein catheterization to analyze liver-directed therapies." The Journal of surgical research 185, 2 (2013): 690-6. [PubMed Link] | [ Full text ]
  • Zaytseva, Y.Y.;Rychahou, P.G.;Gulhati, P.;Elliott, V.A.;Mustain, W.C.;O'Connor, K.;Morris, A.J.;Sunkara, M.;Weiss, H.L.;Lee, E.Y.;Evers, B.M. "Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer." Cancer research 72, 6 (2012): 1504-17. [PubMed Link] | [ Full text ]
  • Haque, F.;Shu, D.;Hu, Y.S.;Shlyakhtenko, L.S.;Rychahou, P.G.;Evers, B.M.;Guo, P. "Ultrastable synergistic tetravalent RNA nanoparticles for targeting to cancers." Nano today 7, 4 (2012): 245-257. [PubMed Link] |
  • Valentino, J.D.;Elliott, V.A.;Zaytseva, Y.Y.;Rychahou, P.G.;Mustain, W.C.;Wang, C.;Gao, T.;Evers, B.M. "Novel small interfering RNA cotargeting strategy as treatment for colorectal cancer." Surgery 152, 2 (2012): 277-85. [PubMed Link] | [ Full text ]
  • Dong, C.;Wu, Y.;Yao, J.;Wang, Y.;Yu, Y.;Rychahou, P.G.;Evers, B.M.;Zhou, B.P. "G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer." The Journal of clinical investigation 122, 4 (2012): 1469-86. [PubMed Link] | [ Full text ]
  • Gulhati, P.;Bowen, K.A.;Liu, J.;Stevens, P.D.;Rychahou, P.G.;Chen, M.;Lee, E.Y.;Weiss, H.L.;O'Connor, K.L.;Gao, T.;Evers, B.M. "mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways." Cancer research 71, 9 (2011): 3246-56. [PubMed Link] | [ Full text ]
  • Mustain, W.C.;Rychahou, P.G.;Evers, B.M. "The role of neurotensin in physiologic and pathologic processes." Current opinion in endocrinology, diabetes, and obesity 18, 1 (2011): 75-82. [PubMed Link] | [ Full text ]
  • Bowen, K.A.;Doan, H.Q.;Zhou, B.P.;Wang, Q.;Zhou, Y.;Rychahou, P.G.;Evers, B.M. "PTEN loss induces epithelial--mesenchymal transition in human colon cancer cells." Anticancer research 29, 11 (2009): 4439-49. [PubMed Link] | [ Full text ]
  • Gulhati, P.;Cai, Q.;Li, J.;Liu, J.;Rychahou, P.G.;Qiu, S.;Lee, E.Y.;Silva, S.R.;Bowen, K.A.;Gao, T.;Evers, B.M. "Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer." Clinical cancer research : an official journal of the American Association for Cancer Research 15, 23 (2009): 7207-16. [PubMed Link] | [ Full text ]