Samuel dos Santos Valenca

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samuelvalenca@uky.edu

Physiology

Position(s):

Post-Doctoral Scholar

Affiliation(s):

Physiology

Selected Publications:

Dimethyl Fumarate Attenuates Lung Inflammation and Oxidative Stress Induced by Chronic Exposure to Diesel Exhaust Particles in Mice. Cattani-Cavalieri I, da Maia Valença H, Moraes JA, Brito-Gitirana L, Romana-Souza B, Schmidt M, Valença SS. Int J Mol Sci. 2020 Dec 18;21(24):9658. doi: 10.3390/ijms21249658.

Eucalyptol promotes lung repair in mice following cigarette smoke-induced emphysema. Kennedy-Feitosa E, Cattani-Cavalieri I, Barroso MV, Romana-Souza B, Brito-Gitirana L, Valenca SS. Phytomedicine. 2019 Mar 1;55:70-79. doi: 10.1016/j.phymed.2018.08.012. Epub 2018 Aug 8.

AT-RVD1 repairs mouse lung after cigarette smoke-induced emphysema via downregulation of oxidative stress by NRF2/KEAP1 pathway. Posso SV, Quesnot N, Moraes JA, Brito-Gitirana L, Kennedy-Feitosa E, Barroso MV, Porto LC, Lanzetti M, Valença SS. Int Immunopharmacol. 2018 Mar;56:330-338. doi: 10.1016/j.intimp.2018.01.045. Epub 2018 Feb 20.

Pharmacological modulation of reactive oxygen species (ROS) improves the airway hyperresponsiveness by shifting the Th1 response in allergic inflammation induced by ovalbumin. Nesi RT, Barroso MV, Souza Muniz V, de Arantes AC, Martins MA, Brito Gitirana L, Neves JS, Benjamim CF, Lanzetti M, Valenca SS. Free Radic Res. 2017 Jul-Aug;51(7-8):708-722. doi: 10.1080/10715762.2017.1364377. Epub 2017 Aug 24.

Eucalyptol attenuates cigarette smoke-induced acute lung inflammation and oxidative stress in the mouse. Kennedy-Feitosa E, Okuro RT, Pinho Ribeiro V, Lanzetti M, Barroso MV, Zin WA, Porto LC, Brito-Gitirana L, Valenca SS. Pulm Pharmacol Ther. 2016 Dec;41:11-18. doi: 10.1016/j.pupt.2016.09.004. Epub 2016 Sep 4.

PubMed Publications:

Cattani-Cavalieri, I ; Valença, SDS ; Schmidt, M. "Nanodomains in cardiopulmonary disorders and the impact of air pollution." Biochemical Society transactions (2020): [PubMed Link] | [ Full text ]
Cattani-Cavalieri, I ; Valença, da Maia; Moraes, JA ; Brito-Gitirana, L ; Romana-Souza, B ; Schmidt, M.; Valença, SS "Dimethyl Fumarate Attenuates Lung Inflammation and Oxidative Stress Induced by Chronic Exposure to Diesel Exhaust Particles in Mice." International journal of molecular sciences 21, 24 (2020): [PubMed Link] | [ Full text ]
Vasconcelos, FM ; Silva, HLA ; Poso, SMV ; Barroso, MV ; Lanzetti, M.; Rocha, RS ; Graça, JS ; Esmerino, EA ; Freitas, MQ ; Silva, MC ; Raices, RSL ; Granato, D ; Pimentel, TC ; Sant'Ana, AS ; Cruz, AG ; Valença, SS "Probiotic Prato cheese attenuates cigarette smoke-induced injuries in mice." Food research international (Ottawa, Ont.) 123, (2019): 697-703. [PubMed Link] | [ Full text ]
Kennedy-Feitosa, E ; Cattani-Cavalieri, I ; Barroso, MV ; Romana-Souza, B ; Brito-Gitirana, L ; Valença, SS "Eucalyptol promotes lung repair in mice following cigarette smoke-induced emphysema." Phytomedicine : international journal of phytotherapy and phytopharmacology 55, (2019): 70-79. [PubMed Link] | [ Full text ]
Valença, SRFA ; Ribeiro-Andrade, M ; Moré, G ; Albuquerque, PPF ; Júnior, JW Pinheiro; Mota, RA "Low prevalence of infection by Sarcocystis neurona in horses from the State of Alagoas, Brazil." Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria 28, 2 (2019): 298-302. [PubMed Link] | [ Full text ]
Zuo, H.; Cattani-Cavalieri, I ; Valença, SS ; Musheshe, N ; Schmidt, M. "Function of cAMP scaffolds in obstructive lung disease: Focus on epithelial-to-mesenchymal transition and oxidative stress." British journal of pharmacology 176, 14 (2019): 2402-2415. [PubMed Link] | [ Full text ]
Barroso, MV ; Graça-Reis, A ; Cattani-Cavalieri, I ; Gitirana, LB ; Valença, SS ; Lanzetti, M. "Mate tea reduces high fat diet-induced liver and metabolic disorders in mice." Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 109, (2019): 1547-1555. [PubMed Link] | [ Full text ]
Cattani-Cavalieri, I ; Valença, SS ; Lanzetti, M.; Carvalho, GMC ; Zin, WA ; Monte-Alto-Costa, A ; Porto, LC ; Romana-Souza, B "Acute Exposure to Diesel-Biodiesel Particulate Matter Promotes Murine Lung Oxidative Stress by Nrf2/HO-1 and Inflammation Through the NF-kB/TNF-α Pathways." Inflammation 42, 2 (2019): 526-537. [PubMed Link] | [ Full text ]
Quesnot, N ; Bucher, S ; Gade, C ; Vlach, M ; Vene, E ; Valença, S ; Gicquel, T ; Holst, H ; Robin, MA ; Loyer, P "Production of chlorzoxazone glucuronides via cytochrome P4502E1 dependent and independent pathways in human hepatocytes." Archives of toxicology 92, 10 (2018): 3077-3091. [PubMed Link] | [ Full text ]
Casquilho, NV ; Moreira-Gomes, MD ; Magalhães, CB ; Okuro, RT ; Ortenzi, VH ; Feitosa-Lima, EK ; Lima, LM ; Barreiro, EJ ; Soares, RM ; Azevedo, SMFO ; Valença, SS ; Fortunato, RS ; Carvalho, AR ; Zin, WA "Oxidative imbalance in mice intoxicated by microcystin-LR can be minimized." Toxicon : official journal of the International Society on Toxinology 144, (2018): 75-82. [PubMed Link] | [ Full text ]
Posso, SV ; Quesnot, N ; Moraes, JA ; Brito-Gitirana, L ; Kennedy-Feitosa, E ; Barroso, MV ; Porto, LC ; Lanzetti, M.; Valença, SS "AT-RVD1 repairs mouse lung after cigarette smoke-induced emphysema via downregulation of oxidative stress by NRF2/KEAP1 pathway." International immunopharmacology 56, (2018): 330-338. [PubMed Link] | [ Full text ]
Freitas-Alves, DR ; Vieira-Monteiro, HA ; Piranda, DN ; Sobral-Leite, M ; da Silva, TSL ; Bergmann, A ; Valença, SS ; Perini, JA ; Vianna-Jorge, R "<i>PTGS2</i> polymorphism rs689466 favors breast cancer recurrence in obese patients." Endocrine-related cancer 25, 3 (2018): 351-365. [PubMed Link] | [ Full text ]
Melo, AC ; Cattani-Cavalieri, I ; Barroso, MV ; Quesnot, N ; Gitirana, LB ; Lanzetti, M.; Valença, SS "Atorvastatin dose-dependently promotes mouse lung repair after emphysema induced by elastase." Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 102, (2018): 160-168. [PubMed Link] | [ Full text ]
Barroso, MV ; Cattani-Cavalieri, I ; de Brito-Gitirana, L ; Fautrel, A ; Lagente, V ; Schmidt, M.; Porto, LC ; Romana-Souza, B ; Valença, SS ; Lanzetti, M. "Propolis reversed cigarette smoke-induced emphysema through macrophage alternative activation independent of Nrf2." Bioorganic & medicinal chemistry 25, 20 (2017): 5557-5568. [PubMed Link] | [ Full text ]
Cattani-Cavalieri, I ; Reis, AG ; Kennedy-Feitosa, E ; Pinho-Ribeiro, V ; Lanzetti, M.; Gitirana, LB ; Romana-Souza, B ; Porto, LC ; Valença, SS "Pulmonary Emphysema Cross-Linking with Pulmonary Fibrosis and Vice Versa: a Non-usual Experimental Intervention with Elastase and Bleomycin." Inflammation 40, 5 (2017): 1487-1496. [PubMed Link] | [ Full text ]
Ribeiro, VM ; Bede, TP ; Rocha, GS ; Barroso, S ; Valença, S ; Azeredo, VB "High fat diet and high polyphenols beverages effects in enzymatic and non-enzymatic antioxidant activity." Nutricion hospitalaria 35, 1 (2017): 169-175. [PubMed Link] | [ Full text ]
Pinho-Ribeiro, V ; Melo, AC ; Kennedy-Feitosa, E ; Graça-Reis, A ; Barroso, MV ; Cattani-Cavalieri, I ; Carvalho, GMC ; Zin, WA ; Porto, LC ; Gitirana, LB ; Lanzetti, M.; Valença, SS "Atorvastatin and Simvastatin Promoted Mouse Lung Repair After Cigarette Smoke-Induced Emphysema." Inflammation 40, 3 (2017): 965-979. [PubMed Link] | [ Full text ]
Nesi, RT ; Barroso, MV ; Muniz, Souza ; Arantes, AC ; Martins, MA ; Gitirana, Brito ; Neves, JS ; Benjamim, CF ; Lanzetti, M.; Valença, SS "Pharmacological modulation of reactive oxygen species (ROS) improves the airway hyperresponsiveness by shifting the Th1 response in allergic inflammation induced by ovalbumin." Free radical research 51, 7-8 (2017): 708-722. [PubMed Link] | [ Full text ]
Nesi, RT ; Kennedy-Feitosa, E ; Lanzetti, M.; Ávila, MB ; Magalhães, CB ; Zin, WA ; Faffe, DS ; Porto, LC ; Valença, SS "Inflammatory and Oxidative Stress Markers in Experimental Allergic Asthma." Inflammation 40, 4 (2017): 1166-1176. [PubMed Link] | [ Full text ]
Carvalho, GM ; Oliveira, VR ; Casquilho, NV ; Araújo, AC ; Soares, RM ; Azevedo, SM ; Pires, KM ; Valença, SS ; Zin, WA "Pulmonary and hepatic injury after sub-chronic exposure to sublethal doses of microcystin-LR." Toxicon : official journal of the International Society on Toxinology 112, (2016): 51-8. [PubMed Link] | [ Full text ]
Victoni, T ; Gicquel, T ; Bodin, A ; Daude, M ; Tenor, H ; Valença, S ; Devillier, P ; Porto, LC ; Lagente, V ; Boichot, E "Roflumilast n-oxide associated with PGE2 prevents the neutrophil elastase-induced production of chemokines by epithelial cells." International immunopharmacology 30, (2016): 1-8. [PubMed Link] | [ Full text ]
Kennedy-Feitosa, E ; Okuro, RT ; Ribeiro, Pinho ; Lanzetti, M.; Barroso, MV ; Zin, WA ; Porto, LC ; Brito-Gitirana, L ; Valença, SS "Eucalyptol attenuates cigarette smoke-induced acute lung inflammation and oxidative stress in the mouse." Pulmonary pharmacology & therapeutics 41, (2016): 11-18. [PubMed Link] | [ Full text ]
Robert, S ; Gicquel, T ; Victoni, T ; Valença, S ; Barreto, E ; Bailly-Maître, B ; Boichot, E ; Lagente, V "Involvement of matrix metalloproteinases (MMPs) and inflammasome pathway in molecular mechanisms of fibrosis." Bioscience reports 36, 4 (2016): [PubMed Link] | [ Full text ]
Trajano, LA ; Trajano, ET ; Lanzetti, M.; Mendonca, MS ; Guilherme, RF ; Figueiredo, RT ; Benjamim, CF ; Valença, SS ; Costa, AM ; Porto, LC "Elastase modifies bleomycin-induced pulmonary fibrosis in mice." Acta histochemica 118, 3 (2016): 203-12. [PubMed Link] | [ Full text ]
Gomes, MD Moreira; Carvalho, GM ; Casquilho, NV ; Araújo, AC ; Valença, SS ; Leal-Cardoso, JH ; Zin, WA "2,2'-Azobis (2-Amidinopropane) Dihydrochloride Is a Useful Tool to Impair Lung Function in Rats." Frontiers in physiology 7, (2016): 475. [PubMed Link] | [ Full text ]
Nesi, RT ; de Souza, PS ; Santos, GP Dos; Thirupathi, A ; Menegali, BT ; Silveira, PC ; da Silva, LA ; Valença, SS ; Pinho, RA "Physical exercise is effective in preventing cigarette smoke-induced pulmonary oxidative response in mice." International journal of chronic obstructive pulmonary disease 11, (2016): 603-10. [PubMed Link] | [ Full text ]
Muzi-Filho, H ; Souza, AM ; Bezerra, CG ; Boldrini, LC ; Takiya, CM ; Oliveira, FL ; Nesi, RT ; Valença, SS ; Silva, AM ; Zapata-Sudo, G ; Sudo, RT ; Einicker-Lamas, M ; Vieyra, A ; Lara, LS ; Cunha, VM "Rats undernourished in utero have altered Ca2+ signaling and reduced fertility in adulthood." Physiological reports 3, 10 (2015): [PubMed Link] | [ Full text ]
Lima, TI ; Monteiro, IC ; Valença, S ; Leal-Cardoso, JH ; Fortunato, RS ; Carvalho, DP ; Teodoro, BG ; Ceccatto, VM "Effect of exercise training on liver antioxidant enzymes in STZ-diabetic rats." Life sciences 128, (2015): 64-71. [PubMed Link] | [ Full text ]
Ferreira, TS ; Lanzetti, M.; Barroso, MV ; Rueff-Barroso, CR ; Benjamim, CF ; de Brito-Gitirana, L ; Porto, LC ; Valença, SS "Oxidative stress and inflammation are differentially affected by atorvastatin, pravastatin, rosuvastatin, and simvastatin on lungs from mice exposed to cigarette smoke." Inflammation 37, 5 (2014): 1355-65. [PubMed Link] | [ Full text ]
Mattos, LJ ; Valença, SS ; Azevedo, SM ; Soares, RM "Dualistic evolution of liver damage in mice triggered by a single sublethal exposure to Microcystin-LR." Toxicon : official journal of the International Society on Toxinology 83, (2014): 43-51. [PubMed Link] | [ Full text ]
Carlos, SP ; Dias, AS ; Júnior, LA Forgiarini; Patricio, PD ; Graciano, T ; Nesi, RT ; Valença, S ; Chiappa, AM ; G, Cipriano ; Souza, CT ; Chiappa, GR "Oxidative damage induced by cigarette smoke exposure in mice: impact on lung tissue and diaphragm muscle." Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 40, 4 (2014): 411-20. [PubMed Link] | [ Full text ]
Mazzoli-Rocha, F ; Carvalho, GM ; Lanzetti, M.; Valença, SS ; Silva, LF ; Saldiva, PH ; Zin, WA ; Faffe, DS "Respiratory toxicity of repeated exposure to particles produced by traffic and sugar cane burning." Respiratory physiology & neurobiology 191, (2014): 106-13. [PubMed Link] | [ Full text ]
Kennedy-Feitosa, E ; Pinto, RF ; Pires, KM ; Monteiro, AP ; Machado, MN ; Santos, JC ; Ribeiro, ML ; Zin, WA ; Canetti, CA ; Romana-Souza, B ; Porto, LC ; Valença, SS "The influence of 5-lipoxygenase on cigarette smoke-induced emphysema in mice." Biochimica et biophysica acta 1840, 1 (2014): 199-208. [PubMed Link] | [ Full text ]
Brogliato, AR ; Borges, PA ; Barros, JF ; Lanzetti, M.; Valença, S ; Oliveira, NC ; Izário-Filho, HJ ; Benjamim, CF "The effect and safety of dressing composed by nylon threads covered with metallic silver in wound treatment." International wound journal 11, 2 (2014): 190-7. [PubMed Link] | [ Full text ]
Victoni, T ; Gleonnec, F ; Lanzetti, M.; Tenor, H ; Valença, S ; Porto, LC ; Lagente, V ; Boichot, E "Roflumilast N-oxide prevents cytokine secretion induced by cigarette smoke combined with LPS through JAK/STAT and ERK1/2 inhibition in airway epithelial cells." PloS one 9, 1 (2014): e85243. [PubMed Link] | [ Full text ]
Alves, JN ; Pires, KM ; Lanzetti, M.; Barroso, MV ; Benjamim, CF ; Costa, CA ; Resende, AC ; Santos, JC ; Ribeiro, ML ; Porto, LC ; Valença, SS "Critical role for CCR2 and HMGB1 in induction of experimental endotoxic shock." Archives of biochemistry and biophysics 537, 1 (2013): 72-81. [PubMed Link] | [ Full text ]
Melo, AC ; Valença, SS ; Gitirana, LB ; Santos, JC ; Ribeiro, ML ; Machado, MN ; Magalhães, CB ; Zin, WA ; Porto, LC "Redox markers and inflammation are differentially affected by atorvastatin, pravastatin or simvastatin administered before endotoxin-induced acute lung injury." International immunopharmacology 17, 1 (2013): 57-64. [PubMed Link] | [ Full text ]
Colombo, R.; Siqueira, R ; Becker, CU ; Fernandes, TG ; Pires, KM ; Valença, SS ; Souza-Rabbo, MP ; Araujo, AS ; Belló-Klein, A "Effects of exercise on monocrotaline-induced changes in right heart function and pulmonary artery remodeling in rats." Canadian journal of physiology and pharmacology 91, 1 (2013): 38-44. [PubMed Link] | [ Full text ]
Valença, RM ; Mota, RA ; Castro, V.; Anderlini, GA ; Júnior, JW Pinheiro; Brandespim, DF ; , ; Guerra, MM "Prevalence and risk factors associated with Leptospira spp. infection in technified swine farms in the state of Alagoas, Brazil: risk factors associated with Leptospira spp. in swine farms." Transboundary and emerging diseases 60, 1 (2013): 79-86. [PubMed Link] | [ Full text ]
Lopes, AA ; Ferreira, TS ; Nesi, RT ; Lanzetti, M.; Pires, KM ; Silva, AM ; Borges, RM ; Silva, AJ ; Valença, SS ; Porto, LC "Antioxidant action of propolis on mouse lungs exposed to short-term cigarette smoke." Bioorganic & medicinal chemistry 21, 24 (2013): 7570-7. [PubMed Link] | [ Full text ]
Muzi-Filho, H ; Bezerra, CG ; Souza, AM ; Boldrini, LC ; Takiya, CM ; Oliveira, FL ; Nesi, RT ; Valença, SS ; Einicker-Lamas, M ; Vieyra, A ; Lara, LS ; Cunha, VM "Undernutrition affects cell survival, oxidative stress, Ca2+ handling and signaling pathways in vas deferens, crippling reproductive capacity." PloS one 8, 7 (2013): e69682. [PubMed Link] | [ Full text ]
Valença, EH ; Souza, AH ; Oliveira, AH ; Valença, SL ; Salvatori, R ; Gonçalves, MI ; Oliveira-Neto, LA ; Barros, AD ; Nascimento, UN ; Oliveira, CR ; Cardoso, DF ; Melo, VA ; Aguiar-Oliveira, MH "Voice quality in short stature with and without GH deficiency." Journal of voice : official journal of the Voice Foundation 26, 5 (2012): 673.e13-9. [PubMed Link] | [ Full text ]
Pires, KM ; Lanzetti, M.; Rueff-Barroso, CR ; Castro, P ; Abrahão, A ; Koatz, VL ; Valença, SS ; Porto, LC "Oxidative damage in alveolar macrophages exposed to cigarette smoke extract and participation of nitric oxide in redox balance." Toxicology in vitro : an international journal published in association with BIBRA 26, 6 (2012): 791-8. [PubMed Link] | [ Full text ]
Oliveira, VR ; Carvalho, GM ; Ávila, MB ; Soares, RM ; Azevedo, SM ; Ferreira, TS ; Valença, SS ; Faffe, DS ; Zin, WA "Time-dependence of lung injury in mice acutely exposed to cylindrospermopsin." Toxicon : official journal of the International Society on Toxinology 60, 5 (2012): 764-72. [PubMed Link] | [ Full text ]
Zin, WA ; Silva, AG ; Magalhães, CB ; Carvalho, GM ; Riva, DR ; Lima, CC ; Leal-Cardoso, JH ; Takiya, CM ; Valença, SS ; Saldiva, PH ; Faffe, DS "Eugenol attenuates pulmonary damage induced by diesel exhaust particles." Journal of applied physiology (Bethesda, Md. : 1985) 112, 5 (2012): 911-7. [PubMed Link] | [ Full text ]
Santos-Silva, MA ; Pires, KM ; Trajano, ET ; Martins, V ; Nesi, RT ; Benjamin, CF ; Caetano, MS ; Sternberg, C.; Machado, MN ; Zin, WA ; Valença, SS ; Porto, LC "Redox imbalance and pulmonary function in bleomycin-induced fibrosis in C57BL/6, DBA/2, and BALB/c mice." Toxicologic pathology 40, 5 (2012): 731-41. [PubMed Link] | [ Full text ]
Pires, KM ; Melo, AC ; Lanzetti, M.; Casquilho, NV ; Zin, WA ; Porto, LC ; Valença, SS "Low tidal volume mechanical ventilation and oxidative stress in healthy mouse lungs." Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 38, 1 (2012): 98-104. [PubMed Link] | [ Full text ]
Ade, da Fonseca; Presta, GA ; Geller, M ; de Paoli, F ; Valença, SS "Low-intensity infrared laser increases plasma proteins and induces oxidative stress in vitro." Lasers in medical science 27, 1 (2012): 211-7. [PubMed Link] | [ Full text ]
Fonseca, AS ; Geller, M ; Filho, Bernardo ; Valença, SS ; de Paoli, F "Low-level infrared laser effect on plasmid DNA." Lasers in medical science 27, 1 (2012): 121-30. [PubMed Link] | [ Full text ]
Moura, RS ; Ferreira, TS ; Lopes, AA ; Pires, KM ; Nesi, RT ; Resende, AC ; Souza, PJ ; Silva, AJ ; Borges, RM ; Porto, LC ; Valença, SS "Effects of Euterpe oleracea Mart. (AÇAÍ) extract in acute lung inflammation induced by cigarette smoke in the mouse." Phytomedicine : international journal of phytotherapy and phytopharmacology 19, 3-4 (2012): 262-9. [PubMed Link] | [ Full text ]
Lanzetti, M.; da Costa, CA ; Nesi, RT ; Barroso, MV ; Martins, V ; Victoni, T ; Lagente, V ; Pires, KM ; Silva, PM e; Resende, AC ; Porto, LC ; Benjamim, CF ; Valença, SS "Oxidative stress and nitrosative stress are involved in different stages of proteolytic pulmonary emphysema." Free radical biology & medicine 53, 11 (2012): 1993-2001. [PubMed Link] | [ Full text ]
Nagato, AC ; Bezerra, FS ; Lanzetti, M.; Lopes, AA ; Silva, MA ; Porto, LC ; Valença, SS "Time course of inflammation, oxidative stress and tissue damage induced by hyperoxia in mouse lungs." International journal of experimental pathology 93, 4 (2012): 269-78. [PubMed Link] | [ Full text ]
Valença, SS ; Rueff-Barroso, CR ; Pimenta, WA ; Melo, AC ; Nesi, RT ; Silva, MA ; Porto, LC "L-NAME and L-arginine differentially ameliorate cigarette smoke-induced emphysema in mice." Pulmonary pharmacology & therapeutics 24, 5 (2011): 587-94. [PubMed Link] | [ Full text ]
Lanzetti, M.; Lopes, AA ; Ferreira, TS ; de Moura, RS ; Resende, AC ; Porto, LC ; Valença, SS "Mate tea ameliorates emphysema in cigarette smoke-exposed mice." Experimental lung research 37, 4 (2011): 246-57. [PubMed Link] | [ Full text ]
Pires, KM ; Bezerra, FS ; Machado, MN ; Zin, WA ; Porto, LC ; Valença, SS "N-(2-mercaptopropionyl)-glycine but not allopurinol prevented cigarette smoke-induced alveolar enlargement in mouse." Respiratory physiology & neurobiology 175, 3 (2011): 322-30. [PubMed Link] | [ Full text ]
Bezerra, FS ; Valença, SS ; Pires, KM ; Lanzetti, M.; Pimenta, WA ; Schmidt, AC ; Porto, LC ; Zin, WA "Long-term exposure to cigarette smoke impairs lung function and increases HMGB-1 expression in mice." Respiratory physiology & neurobiology 177, 2 (2011): 120-6. [PubMed Link] | [ Full text ]
Santos, RS ; Silva, PL ; Oliveira, GP ; Cruz, FF ; Ornellas, DS ; Morales, MM ; Fernandes, J ; Lanzetti, M.; Valença, SS ; Pelosi, P.; Gattass, CR ; Rocco, PR "Effects of oleanolic acid on pulmonary morphofunctional and biochemical variables in experimental acute lung injury." Respiratory physiology & neurobiology 179, 2-3 (2011): 129-36. [PubMed Link] | [ Full text ]
Trajano, ET Lima; Sternberg, C.; Caetano, M ; Silva, MA Santos; Porto, LC ; Santos, JC ; Ribeiro, ML ; Magalhães, CB ; Zin, WA ; Benjamim, CF ; Valença, SS "Endotoxin-induced acute lung injury is dependent upon oxidative response." Inhalation toxicology 23, 14 (2011): 918-26. [PubMed Link] | [ Full text ]
Pires, KM ; Valença, SS ; Resende, AC ; Porto, LC ; Queiroz, EF ; Moreira, DD ; de Moura, RS "Grape skin extract reduced pulmonary oxidative response in mice exposed to cigarette smoke." Medical science monitor : international medical journal of experimental and clinical research 17, 8 (2011): BR187-195. [PubMed Link] | [ Full text ]
Casquilho, NV ; Carvalho, GM ; Alves, JL ; Machado, MN ; Soares, RM ; Azevedo, SM ; Lima, LM ; Barreiro, EJ ; Valença, SS ; Carvalho, AR ; Faffe, DS ; Zin, WA "LASSBio 596 per os avoids pulmonary and hepatic inflammation induced by microcystin-LR." Toxicon : official journal of the International Society on Toxinology 58, 2 (2011): 195-201. [PubMed Link] | [ Full text ]
Riva, DR ; Magalhães, CB ; Lopes, AA ; Lanças, T ; Mauad, T.; Malm, O ; Valença, SS ; Saldiva, PH ; Faffe, DS ; Zin, WA "Low dose of fine particulate matter (PM2.5) can induce acute oxidative stress, inflammation and pulmonary impairment in healthy mice." Inhalation toxicology 23, 5 (2011): 257-67. [PubMed Link] | [ Full text ]
de Moura, RS ; Pires, KM ; Ferreira, Santos ; Lopes, AA ; Nesi, RT ; Resende, AC ; Sousa, PJ ; da Silva, AJ ; Porto, LC ; Valença, SS "Addition of açaí (Euterpe oleracea) to cigarettes has a protective effect against emphysema in mice." Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 49, 4 (2011): 855-63. [PubMed Link] | [ Full text ]
Carvalho, GM ; Oliveira, VR ; Soares, RM ; Azevedo, SM ; Lima, LM ; Barreiro, EJ ; Valença, SS ; Saldiva, PH ; Faffe, DS ; Zin, WA "Can LASSBio 596 and dexamethasone treat acute lung and liver inflammation induced by microcystin-LR?" Toxicon : official journal of the International Society on Toxinology 56, 4 (2010): 604-12. [PubMed Link] | [ Full text ]
Rueff-Barroso, CR ; Trajano, ET ; Alves, JN ; Paiva, RO ; Lanzetti, M.; Pires, KM ; Bezerra, FS ; Pinho, RA ; Valença, SS ; Porto, LC "Organ-related cigarette smoke-induced oxidative stress is strain-dependent." Medical science monitor : international medical journal of experimental and clinical research 16, 7 (2010): BR218-26. [PubMed Link] | [ Full text ]
Martins, V ; Valença, SS ; Farias-Filho, FA ; Molinaro, R.; Simões, RL ; Ferreira, TP ; Silva, PM e; Hogaboam, CM ; Kunkel, SL ; Fierro, IM ; Canetti, C ; Benjamim, CF "ATLa, an aspirin-triggered lipoxin A4 synthetic analog, prevents the inflammatory and fibrotic effects of bleomycin-induced pulmonary fibrosis." Journal of immunology (Baltimore, Md. : 1950) 182, 9 (2009): 5374-81. [PubMed Link] | [ Full text ]
Valença, SS ; Pimenta, WA ; Rueff-Barroso, CR ; Ferreira, TS ; Resende, AC ; Moura, RS ; Porto, LC "Involvement of nitric oxide in acute lung inflammation induced by cigarette smoke in the mouse." Nitric oxide : biology and chemistry 20, 3 (2009): 175-81. [PubMed Link] | [ Full text ]
Castro, P ; Nasser, H ; Abrahão, A ; Reis, LC Dos; Rica, I.; Valença, SS ; Rezende, DC ; Quintas, LE ; Cavalcante, MC ; Porto, LC ; Koatz, VL "Aspirin and indomethacin reduce lung inflammation of mice exposed to cigarette smoke." Biochemical pharmacology 77, 6 (2009): 1029-39. [PubMed Link] | [ Full text ]
Cardoso, JF ; Mendes, FA ; Amadeu, TP ; Romana-Souza, B ; Valença, SS ; Porto, LC ; Abreu, JG ; Monte-Alto-Costa, A "Ccn2/Ctgf overexpression induced by cigarette smoke during cutaneous wound healing is strain dependent." Toxicologic pathology 37, 2 (2009): 175-82. [PubMed Link] | [ Full text ]
Costa, CA ; Amaral, TA ; Carvalho, LC ; Ognibene, DT ; Silva, AF ; Moss, MB ; Valença, SS ; de Moura, RS ; Resende, AC "Antioxidant treatment with tempol and apocynin prevents endothelial dysfunction and development of renovascular hypertension." American journal of hypertension 22, 12 (2009): 1242-9. [PubMed Link] | [ Full text ]
Menegali, BT ; Nesi, RT ; Souza, PS ; Silva, LA ; Silveira, PC ; Valença, SS ; Pinho, RA "The effects of physical exercise on the cigarette smoke-induced pulmonary oxidative response." Pulmonary pharmacology & therapeutics 22, 6 (2009): 567-73. [PubMed Link] | [ Full text ]
Valença, SS ; Bezerra, FS ; Romana-Souza, B ; Paiva, RO ; Costa, AM ; Porto, LC "Supplementation with vitamins C and E improves mouse lung repair." The Journal of nutritional biochemistry 19, 9 (2008): 604-11. [PubMed Link] | [ Full text ]
Valença, SS ; Porto, LC "Immunohistochemical study of lung remodeling in mice exposed to cigarette smoke*." Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 34, 10 (2008): 787-95. [PubMed Link] | [ Full text ]
Valença, SS ; Bezerra, Silva ; Lopes, AA ; Romana-Souza, B ; Cavalcante, MC Marinho; Lima, AB ; Koatz, VL Gonçalves; Porto, LC "Oxidative stress in mouse plasma and lungs induced by cigarette smoke and lipopolysaccharide." Environmental research 108, 2 (2008): 199-204. [PubMed Link] | [ Full text ]
Le Quément, C ; Guénon, I ; Gillon, JY ; Valença, S ; Cayron-Elizondo, V ; Lagente, V ; Boichot, E "The selective MMP-12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke." British journal of pharmacology 154, 6 (2008): 1206-15. [PubMed Link] | [ Full text ]
Lanzetti, M.; Bezerra, FS ; Romana-Souza, B ; Brando-Lima, AC ; Koatz, VL ; Porto, LC ; Valença, SS "Mate tea reduced acute lung inflammation in mice exposed to cigarette smoke." Nutrition (Burbank, Los Angeles County, Calif.) 24, 4 (2008): 375-81. [PubMed Link] | [ Full text ]
Teixeira, KC ; Soares, FS ; Rocha, LG ; Silveira, PC ; Silva, LA ; Valença, SS ; Dal Pizzol, F ; Streck, EL ; Pinho, RA "Attenuation of bleomycin-induced lung injury and oxidative stress by N-acetylcysteine plus deferoxamine." Pulmonary pharmacology & therapeutics 21, 2 (2008): 309-16. [PubMed Link] | [ Full text ]
Cardoso, JF ; Souza, BR ; Amadeu, TP ; Valença, SS ; Porto, LC ; Costa, AM "Effects of cigarette smoke in mice wound healing is strain dependent." Toxicologic pathology 35, 7 (2007): 890-6. [PubMed Link] | [ Full text ]
Valença, SS ; Castro, P ; Pimenta, WA ; Lanzetti, M.; Silva, SV ; Barja-Fidalgo, C ; Koatz, VL ; Porto, LC "Light cigarette smoke-induced emphysema and NFkappaB activation in mouse lung." International journal of experimental pathology 87, 5 (2006): 373-81. [PubMed Link] | [ Full text ]
Bezerra, Silva ; Valença, SS ; Lanzetti, M.; Pimenta, WA ; Castro, P ; Koatz, VL Gonçalves; Porto, LC "Alpha-tocopherol and ascorbic acid supplementation reduced acute lung inflammatory response by cigarette smoke in mouse." Nutrition (Burbank, Los Angeles County, Calif.) 22, 11-12 (2006): 1192-201. [PubMed Link] | [ Full text ]
da Hora, K ; Valença, SS ; Porto, LC "Immunohistochemical study of tumor necrosis factor-alpha, matrix metalloproteinase-12, and tissue inhibitor of metalloproteinase-2 on alveolar macrophages of BALB/c mice exposed to short-term cigarette smoke." Experimental lung research 31, 8 (2005): 759-70. [PubMed Link] | [ Full text ]
Valença, SS ; Lima, EA ; Dire, GF ; Bernardo-Filho, M ; Porto, LC "Sodium pertechnetate (Na99mTcO4) biodistribution in mice exposed to cigarette smoke." BMC nuclear medicine 5, 1 (2005): 1. [PubMed Link] | [ Full text ]
Castro, P ; Legora-Machado, A ; Cardilo-Reis, L ; Valença, S ; Porto, LC ; Walker, C.; Zuany-Amorim, C ; Koatz, VL "Inhibition of interleukin-1beta reduces mouse lung inflammation induced by exposure to cigarette smoke." European journal of pharmacology 498, 1-3 (2004): 279-86. [PubMed Link] | [ Full text ]
Valença, SS ; da Hora, K ; Castro, P ; Moraes, VG ; Carvalho, L ; Porto, LC "Emphysema and metalloelastase expression in mouse lung induced by cigarette smoke." Toxicologic pathology 32, 3 (2004): 351-6. [PubMed Link] | [ Full text ]
Valença, SS ; da Fonseca, de Souza; da Hora, K ; Santos, R ; Porto, LC "Lung morphometry and MMP-12 expression in rats treated with intraperitoneal nicotine." Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 55, 5 (2004): 393-400. [PubMed Link] | [ Full text ]