BMEV222

B. Mark Evers, MD, FACS

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About
Education
Publications

mark.evers@uky.edu

Position(s):

Professor of Surgery

Mark McDowell Cancer Foundation Chair in the Lucille P. Markey Cancer Center

Director, Markey Cancer Center

Physician-In-Chief, Oncology Service

Affiliation(s):

Lucille Parker Markey Cancer Center

Surgery

Other Affiliation(s):

Surgery/General

Surgical Oncology

MD/PhD Program Internal Advisory Committee

MD/PhD Program Mentor

Nutritional Sciences Graduate Faculty

Bio / Education:

Medical School
summa cum laude
University of Tennessee, Memphis, TN

Residency
University of Louisville, Louisville, KY

Fellowship - Research
University of Texas Medical Branch, Galveston, TX

Surgical Interests
Gastrointestinal surgery
Oncology

PubMed Publications:

Guo, L.; Zhang, W.; Xie, Y.; Chen, X.; Olmstead, EE ; Lian, M.; Zhang, B.; Zaytseva, YY ; Evers, BM ; Spielmann, HP ; Liu, X.; Watt, DS ; Liu, C. "Diaminobutoxy-substituted Isoflavonoid (DBI-1) Enhances the Therapeutic Efficacy of GLUT1 Inhibitor BAY-876 by Modulating Metabolic Pathways in Colon Cancer Cells." Molecular cancer therapeutics 21, 5 (2022): 740-750. [PubMed Link] | [ Full text ]
Jiang, H.; Thapa, P ; Ding, N.; Hao, Y.; Alshahrani, A ; Wang, C.; Evers, BM ; Wei, Q. "Sulfiredoxin Promotes Cancer Cell Invasion through Regulation of the miR143-Fascin Axis." Molecular and cellular biology 42, 5 (2022): e0005122. [PubMed Link] | [ Full text ]
Shah, MB ; Rubio, DA Villagomez; Orozco, G ; Desai, S.; Ancheta, A ; Gupta, M.; Mei, X.; Evers, BM ; Gedaly, R.; Cannon, RM "Outcomes in Elderly Patients Undergoing Liver Transplantation Compared with Liver-Directed Ablative Therapy in Early-Stage Hepatocellular Carcinoma." Journal of the American College of Surgeons 234, 5 (2022): 892-899. [PubMed Link] | [ Full text ]
Drury, J ; Rychahou, PG ; Kelson, CO ; Geisen, ME ; Wu, Y.; He, D.; Wang, C.; Lee, EY ; Evers, BM ; Zaytseva, YY "Upregulation of CD36, a Fatty Acid Translocase, Promotes Colorectal Cancer Metastasis by Increasing MMP28 and Decreasing E-Cadherin Expression." Cancers 14, 1 (2022): [PubMed Link] | [ Full text ]
Madabhushi, VV ; RF, Bautista ; Davenport, DL ; Evers, BM ; Judge, JM ; Bhakta, AS "Impact of the Affordable Care Act Medicaid Expansion on Reimbursement in Emergency General Surgery." Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 26, 1 (2022): 191-196. [PubMed Link] | [ Full text ]
Chauhan, A.; Prieur, A ; Kolesar, J.; Arnold, S.; Payen, L ; Mahi, Y ; Vire, B ; Sands, M ; Evers, BM ; Joubert, D ; Anthony, L. "hPG<sub>80</sub> (Circulating Progastrin), a Novel Blood-Based Biomarker for Detection of Poorly Differentiated Neuroendocrine Carcinoma and Well Differentiated Neuroendocrine Tumors." Cancers 14, 4 (2022): [PubMed Link] | [ Full text ]
Wei, R.; Zhou, Y.; Li, C.; Rychahou, P.; Zhang, S.; Titlow, WB ; Bauman, G ; Wu, Y.; Liu, J.; Wang, C.; Weiss, HL ; Evers, BM ; Wang, Q. "Ketogenesis Attenuates KLF5-Dependent Production of CXCL12 to Overcome the Immunosuppressive Tumor Microenvironment in Colorectal Cancer." Cancer research 82, 8 (2022): 1575-1588. [PubMed Link] | [ Full text ]
Rock, SA ; Jiang, K.; Wu, Y.; Liu, Y.; Li, J.; Weiss, HL ; Wang, C.; Jia, J.; Gao, T.; Evers, BM "Neurotensin Regulates Proliferation and Stem Cell Function in the Small Intestine in a Nutrient-Dependent Manner." Cellular and molecular gastroenterology and hepatology 13, 2 (2022): 501-516. [PubMed Link] | [ Full text ]
Araujo, N.; Sledziona, J.; Noothi, SK ; Burikhanov, R.; Hebbar, N.; Ganguly, S.; Shrestha-Bhattarai, T.; Zhu, B.; Katz, WS ; Zhang, Y.; Taylor, BS ; Liu, J.; Chen, L.; Weiss, HL ; He, D.; Wang, C.; Morris, AJ ; Cassis, LA ; Nikolova-Karakashian, M.; Nagareddy, PR ; Melander, O.; Evers, BM ; Kern, PA ; Rangnekar, VM "Tumor Suppressor Par-4 Regulates Complement Factor C3 and Obesity." Frontiers in oncology 12, (2022): 860446. [PubMed Link] | [ Full text ]
Gan, T.; Chen, Q.; Huerta, CT ; Huang, B.; Evers, BM ; Patel, JA "Neoadjuvant Therapy in Stage II/III Rectal Cancer: A Retrospective Study in a Disparate Population and the Effect on Survival." Diseases of the colon and rectum 64, 10 (2021): 1212-1221. [PubMed Link] | [ Full text ]
Jackson, NA ; Gan, T.; Davenport, DL ; Oyler, DR ; Ebbitt, LM ; Evers, BM ; Bhakta, AS "Preoperative opioid, sedative, and antidepressant use is associated with increased postoperative hospital costs in colorectal surgery." Surgical endoscopy 35, 10 (2021): 5599-5606. [PubMed Link] | [ Full text ]
Xie, Y.; Zhang, W.; Guo, L.; Kril, LM ; Begley, KL ; Sviripa, VM ; Chen, X.; Liu, X.; Lee, EY ; He, D.; Wang, C.; Gao, T.; Liu, X.; Evers, BM ; Watt, DS ; Liu, C. "Potent Synergistic Effect on C-Myc-Driven Colorectal Cancers Using a Novel Indole-Substituted Quinoline with a Plk1 Inhibitor." Molecular cancer therapeutics 20, 10 (2021): 1893-1903. [PubMed Link] | [ Full text ]
Chow, Z ; Johnson, J.; Chauhan, A.; Izumi, T.; Cavnar, M ; Weiss, H.; Townsend CM, Jr ; Anthony, L.; Wasilchenko, C ; Melton, ML ; Schrader, J.; Evers, BM ; Rychahou, P. "PI3K/mTOR Dual Inhibitor PF-04691502 Is a Schedule-Dependent Radiosensitizer for Gastroenteropancreatic Neuroendocrine Tumors." Cells 10, 5 (2021): [PubMed Link] | [ Full text ]
Li, J.; Song, J.; Yan, B.; Weiss, HL ; Weiss, LT ; Gao, T.; Evers, BM "Neurotensin differentially regulates bile acid metabolism and intestinal FXR-bile acid transporter axis in response to nutrient abundance." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 35, 5 (2021): e21371. [PubMed Link] | [ Full text ]
DeCoster, RC ; Lynch, EB ; Bonaroti, AR ; Webster, JM ; Butterfield, TA ; Evers, BM ; Vasconez, HC ; Clemens, MW "Breast Implant-associated Anaplastic Large Cell Lymphoma: An Evidence-based Systematic Review." Annals of surgery 273, 3 (2021): 449-458. [PubMed Link] | [ Full text ]
Chow, Z ; Osterhaus, P ; Huang, B.; Chen, Q.; Schoenberg, N.; Dignan, M.; Evers, BM ; Bhakta, A. "Factors Contributing to Delay in Specialist Care After Colorectal Cancer Diagnosis in Kentucky." The Journal of surgical research 259, (2021): 420-430. [PubMed Link] | [ Full text ]
Chang, YW ; Murphy, K.; Yackzan, D ; Thomas, S.; Kay, D ; Davenport, D.; Evers, BM ; Bhakta, AS "Abdominal Wall Thickness is a Predictor for Surgical Site Infections in Patients Undergoing Colorectal Operations." The American surgeon 87, 7 (2021): 1155-1162. [PubMed Link] | [ Full text ]
Tucker, TC ; Charlton, ME ; Schroeder, MC ; Jacob, J.; Tolle, CL ; Evers, BM ; Mullett, TW "Improving the Quality of Cancer Care in Community Hospitals." Annals of surgical oncology 28, 2 (2021): 632-638. [PubMed Link] | [ Full text ]
Kim, JT ; Napier, DL ; Kim, J.; Li, C.; Lee, EY ; Weiss, HL ; Wang, Q.; Evers, BM "Ketogenesis alleviates TNFα-induced apoptosis and inflammatory responses in intestinal cells." Free radical biology & medicine 172, (2021): 90-100. [PubMed Link] | [ Full text ]
Reichel, D.; Curtis, LT ; Ehlman, E ; Evers, BM ; Rychahou, P.; Frieboes, HB ; Bae, Y. "Correction to: Development of Halofluorochromic Polymer Nanoassemblies for the Potential Detection of Liver Metastatic Colorectal Cancer Tumors Using Experimental and Computational Approaches." Pharmaceutical research 38, 8 (2021): 1467. [PubMed Link] | [ Full text ]
Gan, T.; Schaberg, KB ; He, D.; Mansour, A ; Kapoor, H ; Wang, C.; Evers, BM ; Bocklage, TJ "Association Between Obesity and Histological Tumor Budding in Patients With Nonmetastatic Colon Cancer." JAMA network open 4, 4 (2021): e213897. [PubMed Link] | [ Full text ]
Li, C.; Zhou, Y.; Kim, JT ; Sengoku, T.; Alstott, MC ; Weiss, HL ; Wang, Q.; Evers, BM "Regulation of SIRT2 by Wnt/β-catenin signaling pathway in colorectal cancer cells." Biochimica et biophysica acta. Molecular cell research 1868, 4 (2021): 118966. [PubMed Link] | [ Full text ]
Johnson, J.; Chow, Z ; Lee, E.; Weiss, HL ; Evers, BM ; Rychahou, P. "Role of AMPK and Akt in triple negative breast cancer lung colonization." Neoplasia (New York, N.Y.) 23, 4 (2021): 429-438. [PubMed Link] | [ Full text ]
Qiu, Z.; Dong, B.; Guo, W.; Piotr, R ; Longmore, G ; Yang, X.; Yu, Z.; Deng, J.; Evers, BM ; Wu, Y. "STK39 promotes breast cancer invasion and metastasis by increasing SNAI1 activity upon phosphorylation." Theranostics 11, 16 (2021): 7658-7670. [PubMed Link] | [ Full text ]
Xiong, X.; Wen, YA ; Fairchild, R ; Zaytseva, YY ; Weiss, HL ; Evers, BM ; Gao, T. "Upregulation of CPT1A is essential for the tumor-promoting effect of adipocytes in colon cancer." Cell death & disease 11, 9 (2020): 736. [PubMed Link] | [ Full text ]
Gan, T.; Stevens, AT ; Xiong, X.; Wen, YA ; Farmer, TN ; Li, AT ; Stevens, PD ; Golshani, S ; Weiss, HL ; Evers, BM ; Gao, T. "Inhibition of protein tyrosine phosphatase receptor type F suppresses Wnt signaling in colorectal cancer." Oncogene 39, 44 (2020): 6789-6801. [PubMed Link] | [ Full text ]
Li, L.; Weiss, HL ; Li, J.; Chen, Z.; Donato, L ; Evers, BM "High plasma levels of pro-NT are associated with increased colon cancer risk." Endocrine-related cancer 27, 11 (2020): 641-646. [PubMed Link] | [ Full text ]
Johnson, J.; Chow, Z ; Napier, D.; Lee, E.; Weiss, HL ; Evers, BM ; Rychahou, P. "Targeting PI3K and AMPKα Signaling Alone or in Combination to Enhance Radiosensitivity of Triple Negative Breast Cancer." Cells 9, 5 (2020): [PubMed Link] | [ Full text ]
Guo, Y.; Ye, Q.; Deng, P.; Cao, Y.; He, D.; Zhou, Z.; Wang, C.; Zaytseva, YY ; Schwartz, CE ; Lee, EY ; Evers, BM ; Morris, AJ ; Liu, S.; She, QB "Spermine synthase and MYC cooperate to maintain colorectal cancer cell survival by repressing Bim expression." Nature communications 11, 1 (2020): 3243. [PubMed Link] | [ Full text ]
Li, J.; Li, X.; Song, J.; Yan, B.; Rock, SA ; Jia, J.; Liu, J.; Wang, C.; Weiss, T.; Weiss, HL ; Gao, T.; Alam, A ; Evers, BM "Absence of neurotensin attenuates intestinal dysbiosis and inflammation by maintaining Mmp7/α-defensin axis in diet-induced obese mice." FASEB journal : official publication of the Federation of American Societies for Experimental Biology 34, 6 (2020): 8596-8610. [PubMed Link] | [ Full text ]
Gan, T.; Jackson, NA ; Castle, JT ; Davenport, DL ; Oyler, DR ; Ebbitt, LM ; Evers, BM ; Bhakta, AS "A Retrospective Review: Patient-Reported Preoperative Prescription Opioid, Sedative, or Antidepressant Use Is Associated with Worse Outcomes in Colorectal Surgery." Diseases of the colon and rectum 63, 7 (2020): 965-973. [PubMed Link] | [ Full text ]
Wang, J.; Yu, Q.; Qiu, Z.; Dai, T.; Wang, S.; Yang, X.; Evers, BM ; Wu, Y. "The combined effect of epigenetic inhibitors for LSD1 and BRD4 alters prostate cancer growth and invasion." Aging 12, 1 (2020): 397-415. [PubMed Link] | [ Full text ]
Guo, S.; Vieweger, M.; Zhang, K.; Yin, H.; Wang, H.; Li, X.; Li, S.; Hu, S.; Sparreboom, A ; Evers, BM ; Dong, Y.; Chiu, W.; Guo, P. "Ultra-thermostable RNA nanoparticles for solubilizing and high-yield loading of paclitaxel for breast cancer therapy." Nature communications 11, 1 (2020): 972. [PubMed Link] | [ Full text ]
Turcios, L.; Marti, F.; Watt, DS ; Kril, LM ; Khurana, A.; Chapelin, F ; Liu, C.; Zwischenberger, JB ; Evers, BM ; Gedaly, R. "Mitochondrial uncoupling and the disruption of the metabolic network in hepatocellular carcinoma." Oncotarget 11, 31 (2020): 3013-3024. [PubMed Link] | [ Full text ]
Chauhan, A.; El-Khouli, R ; Waits, T ; Agrawal, R.; Siddiqui, F ; Tarter, Z ; Horn, M.; Weiss, H.; Oates, E ; Evers, BM ; Anthony, L. "Post FDA approval analysis of 200 gallium-68 DOTATATE imaging: A retrospective analysis in neuroendocrine tumor patients." Oncotarget 11, 32 (2020): 3061-3068. [PubMed Link] | [ Full text ]
Gan, T.; Huang, B.; Chen, Q.; McGrath, PC ; Evers, BM ; Marcinkowski, EF "Postmastectomy Radiotherapy: Barriers to Implementation in a Disparate Population." The American surgeon 86, 4 (2020): 377-385. [PubMed Link] |
Chow, Z ; Gan, T.; Chen, Q.; Huang, B.; Schoenberg, N.; Dignan, M.; Evers, BM ; Bhakta, AS "Nonadherence to Standard of Care for Locally Advanced Colon Cancer as a Contributory Factor for High Mortality Rates in Kentucky." Journal of the American College of Surgeons 230, 4 (2020): 428-439. [PubMed Link] | [ Full text ]
Li, C.; Zhou, Y.; Rychahou, P.; Weiss, HL ; Lee, EY ; Perry, CL ; Barrett, TA ; Wang, Q.; Evers, BM "SIRT2 Contributes to the Regulation of Intestinal Cell Proliferation and Differentiation." Cellular and molecular gastroenterology and hepatology 10, 1 (2020): 43-57. [PubMed Link] | [ Full text ]
Drury, J ; Rychahou, PG ; He, D.; Jafari, N.; Wang, C.; Lee, EY ; Weiss, HL ; Evers, BM ; Zaytseva, YY "Inhibition of Fatty Acid Synthase Upregulates Expression of CD36 to Sustain Proliferation of Colorectal Cancer Cells." Frontiers in oncology 10, (2020): 1185. [PubMed Link] | [ Full text ]
Noto, FK ; Sangodkar, J ; Adedeji, BT ; Moody, S ; McClain, CB ; Tong, M.; Ostertag, E ; Crawford, J.; Gao, X.; Hurst, L ; O'Connor, CM ; Hanson, EN ; Izadmehr, S ; Tohmé, R ; Narla, J ; LeSueur, K ; Bhattacharya, K ; Rupani, A ; Tayeh, MK ; Innis, JW ; Galsky, MD ; Evers, BM ; DiFeo, A ; Narla, G ; Jamling, TY "The SRG rat, a Sprague-Dawley Rag2/Il2rg double-knockout validated for human tumor oncology studies." PloS one 15, 10 (2020): e0240169. [PubMed Link] | [ Full text ]
Burkeen, G ; Chauhan, A.; Agrawal, R.; Raiker, R ; Kolesar, J.; Anthony, L.; Evers, BM ; Arnold, S. "Gynecologic large cell neuroendocrine carcinoma: A review." Rare tumors 12, (2020): 2036361320968401. [PubMed Link] | [ Full text ]
Kim, JT ; Li, C.; Weiss, HL ; Zhou, Y.; Liu, C.; Wang, Q.; Evers, BM "Regulation of Ketogenic Enzyme HMGCS2 by Wnt/β-catenin/PPARγ Pathway in Intestinal Cells." Cells 8, 9 (2019): [PubMed Link] | [ Full text ]
Raiker, R ; Chauhan, A.; Hasanein, H ; Burkeen, G ; Horn, M.; Veedu, J ; Vela, C ; Arnold, S.; Kolesar, J.; Anthony, L.; Evers, BM ; Cavnar, M "Biliary tract large cell neuroendocrine carcinoma: current evidence." Orphanet journal of rare diseases 14, 1 (2019): 266. [PubMed Link] | [ Full text ]
Liu, L.; Qi, L.; Knifley, T.; Piecoro, DW ; Rychahou, P.; Liu, J.; Mitov, MI ; Martin, J.; Wang, C.; Wu, J.; Weiss, HL ; Butterfield, DA ; Evers, BM ; O'Connor, KL ; Chen, M. "S100A4 alters metabolism and promotes invasion of lung cancer cells by up-regulating mitochondrial complex I protein NDUFS2." The Journal of biological chemistry 294, 18 (2019): 7516-7527. [PubMed Link] | [ Full text ]
Chauhan, A.; Farooqui, Z.; Silva, SR ; Murray, A.; Hodges, KB ; Yu, Q.; Myint, ZW ; Raajesekar, AK ; Weiss, H.; Arnold, S.; Evers, BM ; Anthony, L. "Integrating a 92-Gene Expression Analysis for the Management of Neuroendocrine Tumors of Unknown Primary" Asian Pacific journal of cancer prevention : APJCP 20, 1 (2019): 113-116. [PubMed Link] | [ Full text ]
Jafari, N.; Drury, J ; Morris, AJ ; Onono, FO ; Stevens, PD ; Gao, T.; Liu, J.; Wang, C.; Lee, EY ; Weiss, HL ; Evers, BM ; Zaytseva, YY "<i>De Novo</i> Fatty Acid Synthesis-Driven Sphingolipid Metabolism Promotes Metastatic Potential of Colorectal Cancer." Molecular cancer research : MCR 17, 1 (2019): 140-152. [PubMed Link] | [ Full text ]
DeCoster, RC ; Bautista, RF ; Evers, BM "Comment on "Training the Surgeon-Scientist in Today's Healthcare Environment"." Annals of surgery 270, 6 (2019): e124-e125. [PubMed Link] | [ Full text ]
Gan, T.; Sinner, HF ; Walling, SC ; Chen, Q.; Huang, B.; Tucker, TC ; Patel, JA ; Evers, BM ; Bhakta, AS "Impact of the Affordable Care Act on Colorectal Cancer Screening, Incidence, and Survival in Kentucky." Journal of the American College of Surgeons 228, 4 (2019): 342-353.e1. [PubMed Link] | [ Full text ]
Rock, S.; Li, X.; Song, J.; Townsend CM, Jr ; Weiss, HL ; Rychahou, P.; Gao, T.; Li, J.; Evers, BM "Kinase suppressor of Ras 1 and Exo70 promote fatty acid-stimulated neurotensin secretion through ERK1/2 signaling." PloS one 14, 3 (2019): e0211134. [PubMed Link] | [ Full text ]
Johnson, J.; Rychahou, P.; Sviripa, VM ; Weiss, HL ; Liu, C.; Watt, DS ; Evers, BM "Induction of AMPK activation by N,N'-diarylurea FND-4b decreases growth and increases apoptosis in triple negative and estrogen-receptor positive breast cancers." PloS one 14, 3 (2019): e0209392. [PubMed Link] | [ Full text ]
Sinner, HF ; Johnson, J.; Rychahou, PG ; Watt, DS ; Zaytseva, YY ; Liu, C.; Evers, BM "Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation." PloS one 14, 10 (2019): e0224253. [PubMed Link] | [ Full text ]
Frohman, HA ; Rychahou, PG ; Li, J.; Gan, T.; Evers, BM "Development of murine bariatric surgery models: lessons learned." The Journal of surgical research 229, (2018): 302-310. [PubMed Link] | [ Full text ]
Wang, Q.; Zhou, Y.; Rychahou, P.; Harris, JW ; Zaytseva, YY ; Liu, J.; Wang, C.; Weiss, HL ; Liu, C.; Lee, EY ; Evers, BM "Deptor Is a Novel Target of Wnt/β-Catenin/c-Myc and Contributes to Colorectal Cancer Cell Growth." Cancer research 78, 12 (2018): 3163-3175. [PubMed Link] | [ Full text ]
Pi, F.; Binzel, DW ; Lee, TJ ; Li, Z.; Sun, M.; Rychahou, P.; Li, H.; Haque, F.; Wang, S.; Croce, CM ; Guo, B.; Evers, BM ; Guo, P. "Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression." Nature nanotechnology 13, 1 (2018): 82-89. [PubMed Link] | [ Full text ]
Wen, YA ; Xiong, X.; Zaytseva, YY ; Napier, DL ; Vallee, E.; Li, AT ; Wang, C.; Weiss, HL ; Evers, BM ; Gao, T. "Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer." Cell death & disease 9, 3 (2018): 265. [PubMed Link] | [ Full text ]
Kim, JT ; Napier, DL ; Weiss, HL ; Lee, EY ; Townsend CM, Jr ; Evers, BM "Neurotensin Receptor 3/Sortilin Contributes to Tumorigenesis of Neuroendocrine Tumors Through Augmentation of Cell Adhesion and Migration." Neoplasia (New York, N.Y.) 20, 2 (2018): 175-181. [PubMed Link] | [ Full text ]
Liu, J.; Duan, Z.; Guo, W.; Zeng, L.; Wu, Y.; Chen, Y.; Tai, F ; Wang, Y.; Lin, Y.; Zhang, Q.; He, Y.; Deng, J.; Stewart, RL ; Wang, C.; Lin, PC ; Ghaffari, S ; Evers, BM ; Liu, S.; Zhou, MM ; Zhou, BP ; Shi, J. "Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer." Nature communications 9, 1 (2018): 5200. [PubMed Link] | [ Full text ]
Li, J.; Song, J.; Li, X.; Rock, SB ; Sinner, HF ; Weiss, HL ; Weiss, T.; Townsend CM, Jr ; Gao, T.; Evers, BM "FFAR4 Is Involved in Regulation of Neurotensin Release From Neuroendocrine Cells and Male C57BL/6 Mice." Endocrinology 159, 8 (2018): 2939-2952. [PubMed Link] | [ Full text ]
Chauhan, A.; Farooqui, Z.; Murray, LA ; Weiss, HL ; War Myint, Z.; Raajasekar, AKA ; Evers, BM ; Arnold, S.; Anthony, L. "Capecitabine and Temozolomide in Neuroendocrine Tumor of Unknown Primary." Journal of oncology 2018, (2018): 3519247. [PubMed Link] | [ Full text ]
Lin, Y.; Wang, Y.; Shi, Q.; Yu, Q.; Liu, C.; Feng, J.; Deng, J.; Evers, BM ; Zhou, BP ; Wu, Y. "Stabilization of the transcription factors slug and twist by the deubiquitinase dub3 is a key requirement for tumor metastasis." Oncotarget 8, 43 (2017): 75127-75140. [PubMed Link] | [ Full text ]
Mitov, MI ; Harris, JW ; Alstott, MC ; Zaytseva, YY ; Evers, BM ; Butterfield, DA "Temperature induces significant changes in both glycolytic reserve and mitochondrial spare respiratory capacity in colorectal cancer cell lines." Experimental cell research 354, 2 (2017): 112-121. [PubMed Link] | [ Full text ]
Kenlan, DE ; Rychahou, P.; Sviripa, VM ; Weiss, HL ; Liu, C.; Watt, DS ; Evers, BM "Fluorinated N,N'-Diarylureas As Novel Therapeutic Agents Against Cancer Stem Cells." Molecular cancer therapeutics 16, 5 (2017): 831-837. [PubMed Link] | [ Full text ]
Wang, Q.; Zhou, Y.; Rychahou, P.; Fan, TW ; Lane, AN ; Weiss, HL ; Evers, BM "Ketogenesis contributes to intestinal cell differentiation." Cell death and differentiation 24, 3 (2017): 458-468. [PubMed Link] | [ Full text ]
Kim, JT ; Weiss, HL ; Evers, BM "Diverse expression patterns and tumorigenic role of neurotensin signaling components in colorectal cancer cells." International journal of oncology 50, 6 (2017): 2200-2206. [PubMed Link] | [ Full text ]
Wu, Y.; Wang, Y.; Lin, Y.; Liu, Y.; Wang, Y.; Jia, J.; Singh, P.; Chi, YI ; Wang, C.; Dong, C.; Li, W.; Tao, M.; Napier, D.; Shi, Q.; Deng, J.; Evers, BM ; Zhou, BP "Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation." Nature communications 8, (2017): 14228. [PubMed Link] | [ Full text ]
Wang, J.; Ye, Q.; Cao, Y.; Guo, Y.; Huang, X.; Mi, W.; Liu, S.; Wang, C.; Yang, HS ; Zhou, BP ; Evers, BM ; She, QB "Snail determines the therapeutic response to mTOR kinase inhibitors by transcriptional repression of 4E-BP1." Nature communications 8, 1 (2017): 2207. [PubMed Link] | [ Full text ]
Gao, T.; Evers, BM "Colorectal cancer: A new innate immune sensor - functions from inside the colonic epithelium." Nature reviews. Gastroenterology & hepatology 14, 4 (2017): 199-200. [PubMed Link] | [ Full text ]
Li, J.; Song, J.; Zaytseva, YY ; Liu, Y.; Rychahou, P.; Jiang, K.; Starr, ME ; Kim, JT ; Harris, JW ; Yiannikouris, FB ; Katz, WS ; Nilsson, PM ; Orho-Melander, M.; Chen, J.; Zhu, H.; Fahrenholz, T.; Higashi, RM ; Gao, T.; Morris, AJ ; Cassis, LA ; Fan, TW ; Weiss, HL ; Dobner, PR ; Melander, O.; Jia, J.; Evers, BM "An obligatory role for neurotensin in high-fat-diet-induced obesity." Nature 533, 7603 (2016): 411-5. [PubMed Link] | [ Full text ]
Yu, T.; Chen, X.; Lin, T.; Liu, J.; Li, M.; Zhang, W.; Xu, X.; Zhao, W.; Liu, M.; Napier, DL ; Wang, C.; Evers, BM ; Liu, C. "KLF4 deletion alters gastric cell lineage and induces MUC2 expression." Cell death & disease 7, 6 (2016): e2255. [PubMed Link] | [ Full text ]
Upreti, M.; Jyoti, A.; Johnson, SE ; Swindell, EP ; Napier, D.; Sethi, P.; Chan, R.; Feddock, JM ; Weiss, HL ; O'Halloran, TV ; Evers, BM "Radiation-enhanced therapeutic targeting of galectin-1 enriched malignant stroma in triple negative breast cancer." Oncotarget 7, 27 (2016): 41559-41574. [PubMed Link] | [ Full text ]
Li, J.; Song, J.; Weiss, HL ; Weiss, T.; Townsend CM, Jr ; Evers, BM "Activation of AMPK Stimulates Neurotensin Secretion in Neuroendocrine Cells." Molecular endocrinology (Baltimore, Md.) 30, 1 (2016): 26-36. [PubMed Link] | [ Full text ]
Jiang, K.; Liu, Y.; Fan, J.; Zhang, J.; Li, XA ; Evers, BM ; Zhu, H.; Jia, J. "PI(4)P Promotes Phosphorylation and Conformational Change of Smoothened through Interaction with Its C-terminal Tail." PLoS biology 14, 2 (2016): e1002375. [PubMed Link] | [ Full text ]
Vilchez, V.; Turcios, L.; Zaytseva, Y.; Stewart, R.; Lee, EY ; Maynard, E.; Shah, MB ; Daily, MF ; Tzeng, CW ; Davenport, D.; Castellanos, AL ; Krohmer, S.; Hosein, PJ ; Evers, BM ; Gedaly, R. "Cancer stem cell marker expression alone and in combination with microvascular invasion predicts poor prognosis in patients undergoing transplantation for hepatocellular carcinoma." American journal of surgery 212, 2 (2016): 238-45. [PubMed Link] | [ Full text ]
Sharma, A.; Haque, F.; Pi, F.; Shlyakhtenko, LS ; Evers, BM ; Guo, P. "Controllable self-assembly of RNA dendrimers." Nanomedicine : nanotechnology, biology, and medicine 12, 3 (2016): 835-844. [PubMed Link] | [ Full text ]
Kim, JT ; Li, J.; Song, J.; Lee, EY ; Weiss, HL ; Townsend CM, Jr ; Evers, BM "Differential expression and tumorigenic function of neurotensin receptor 1 in neuroendocrine tumor cells." Oncotarget 6, 29 (2015): 26960-70. [PubMed Link] | [ Full text ]
Wydra, RJ ; Rychahou, PG ; Evers, BM ; Anderson, KW ; Dziubla, TD ; Hilt, JZ "The role of ROS generation from magnetic nanoparticles in an alternating magnetic field on cytotoxicity." Acta biomaterialia 25, (2015): 284-90. [PubMed Link] | [ Full text ]
Kim, JT ; Liu, C.; Zaytseva, YY ; Weiss, HL ; Townsend CM, Jr ; Evers, BM "Neurotensin, a novel target of Wnt/β-catenin pathway, promotes growth of neuroendocrine tumor cells." International journal of cancer 136, 6 (2015): 1475-81. [PubMed Link] | [ Full text ]
Starr, ME ; Takahashi, H.; Okamura, D.; Zwischenberger, BA ; Mrazek, AA ; Ueda, J.; Stromberg, AJ ; Evers, BM ; Esmon, CT ; Saito, H. "Increased coagulation and suppressed generation of activated protein C in aged mice during intra-abdominal sepsis." American journal of physiology. Heart and circulatory physiology 308, 2 (2015): H83-91. [PubMed Link] | [ Full text ]
Zhou, Y.; Rychahou, P.; Wang, Q.; Weiss, HL ; Evers, BM "TSC2/mTORC1 signaling controls Paneth and goblet cell differentiation in the intestinal epithelium." Cell death & disease 6, (2015): e1631. [PubMed Link] | [ Full text ]
Rychahou, P.; Haque, F.; Shu, Y ; Zaytseva, Y.; Weiss, HL ; Lee, EY ; Mustain, W.; Valentino, J.; Guo, P.; Evers, BM "Delivery of RNA nanoparticles into colorectal cancer metastases following systemic administration." ACS nano 9, 2 (2015): 1108-16. [PubMed Link] | [ Full text ]
Starr, ME ; Saito, M.; Evers, BM ; Saito, H. "Age-Associated Increase in Cytokine Production During Systemic Inflammation-II: The Role of IL-1β in Age-Dependent IL-6 Upregulation in Adipose Tissue." The journals of gerontology. Series A, Biological sciences and medical sciences 70, 12 (2015): 1508-15. [PubMed Link] | [ Full text ]
Zaytseva, YY ; Harris, JW ; Mitov, MI ; Kim, JT ; Butterfield, DA ; Lee, EY ; Weiss, HL ; Gao, T.; Evers, BM "Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respiration." Oncotarget 6, 22 (2015): 18891-904. [PubMed Link] | [ Full text ]
Li, H.; Rychahou, PG ; Cui, Z.; Pi, F.; Evers, BM ; Shu, D.; Guo, P.; Luo, W. "RNA Nanoparticles Derived from Three-Way Junction of Phi29 Motor pRNA Are Resistant to I-125 and Cs-131 Radiation." Nucleic acid therapeutics 25, 4 (2015): 188-97. [PubMed Link] | [ Full text ]
Zhu, J.; Xiong, G.; Fu, H.; Evers, BM ; Zhou, BP ; Xu, R. "Chaperone Hsp47 Drives Malignant Growth and Invasion by Modulating an ECM Gene Network." Cancer research 75, 8 (2015): 1580-91. [PubMed Link] | [ Full text ]
Evers, BM "The evolving role of the surgeon scientist." Journal of the American College of Surgeons 220, 4 (2015): 387-95. [PubMed Link] | [ Full text ]
Rychahou, P.; Shu, Y ; Haque, F.; Hu, J.; Guo, P.; Evers, BM "Methods and assays for specific targeting and delivery of RNA nanoparticles to cancer metastases." Methods in molecular biology (Clifton, N.J.) 1297, (2015): 121-35. [PubMed Link] | [ Full text ]
Zhou, Y.; Wang, Q.; Weiss, HL ; Evers, BM "Nuclear factor of activated T-cells 5 increases intestinal goblet cell differentiation through an mTOR/Notch signaling pathway." Molecular biology of the cell 25, 18 (2014): 2882-90. [PubMed Link] | [ Full text ]
Bailey, MB ; Davenport, DL ; Vargas, HD ; Evers, BM ; McKenzie, SP "Longer operative time: deterioration of clinical outcomes of laparoscopic colectomy versus open colectomy." Diseases of the colon and rectum 57, 5 (2014): 616-22. [PubMed Link] | [ Full text ]
Valentino, JD ; Li, J.; Zaytseva, YY ; Mustain, WC ; Elliott, VA ; Kim, JT ; Harris, JW ; Campbell, K.; Weiss, H.; Wang, C.; Song, J.; Anthony, L.; Townsend CM, Jr ; Evers, BM "Cotargeting the PI3K and RAS pathways for the treatment of neuroendocrine tumors." Clinical cancer research : an official journal of the American Association for Cancer Research 20, 5 (2014): 1212-22. [PubMed Link] | [ Full text ]
Hollis, CP ; Weiss, HL ; Evers, BM ; Gemeinhart, RA ; Li, T. "In vivo investigation of hybrid Paclitaxel nanocrystals with dual fluorescent probes for cancer theranostics." Pharmaceutical research 31, 6 (2014): 1450-9. [PubMed Link] | [ Full text ]
McKenzie, SP ; Vargas, HD ; Evers, BM ; Davenport, DL "Selection criteria for combined resection of synchronous colorectal cancer hepatic metastases: a cautionary note." International journal of colorectal disease 29, 6 (2014): 729-35. [PubMed Link] | [ Full text ]
Zaytseva, YY ; Elliott, VA ; Rychahou, P.; Mustain, WC ; Kim, JT ; Valentino, J.; Gao, T.; O'Connor, KL ; Neltner, JM ; Lee, EY ; Weiss, HL ; Evers, BM "Cancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer." Carcinogenesis 35, 6 (2014): 1341-51. [PubMed Link] | [ Full text ]
Shi, J.; Wang, Y.; Zeng, L.; Wu, Y.; Deng, J.; Zhang, Q.; Lin, Y.; Li, J.; Kang, T.; Tao, M.; Rusinova, E.; Zhang, G.; Wang, C.; Zhu, H.; Yao, J.; Zeng, YX ; Evers, BM ; Zhou, MM ; Zhou, BP "Disrupting the interaction of BRD4 with diacetylated Twist suppresses tumorigenesis in basal-like breast cancer." Cancer cell 25, 2 (2014): 210-25. [PubMed Link] | [ Full text ]
Shu, Y ; Pi, F.; Sharma, A.; Rajabi, M.; Haque, F.; Shu, D.; Leggas, M.; Evers, BM ; Guo, P. "Stable RNA nanoparticles as potential new generation drugs for cancer therapy." Advanced drug delivery reviews 66, (2014): 74-89. [PubMed Link] | [ Full text ]
Ye, Q.; Cai, W.; Zheng, Y.; Evers, BM ; She, QB "ERK and AKT signaling cooperate to translationally regulate survivin expression for metastatic progression of colorectal cancer." Oncogene 33, 14 (2014): 1828-39. [PubMed Link] | [ Full text ]
Gedaly, R.; Galuppo, R.; Daily, MF ; Shah, M.; Maynard, E.; Chen, C.; Zhang, X.; Esser, KA ; Cohen, DA ; Evers, BM ; Jiang, J.; Spear, BT "Targeting the Wnt/β-catenin signaling pathway in liver cancer stem cells and hepatocellular carcinoma cell lines with FH535." PloS one 9, 6 (2014): e99272. [PubMed Link] | [ Full text ]
Elliott, VA ; Rychahou, P.; Zaytseva, YY ; Evers, BM "Activation of c-Met and upregulation of CD44 expression are associated with the metastatic phenotype in the colorectal cancer liver metastasis model." PloS one 9, 5 (2014): e97432. [PubMed Link] | [ Full text ]
Starr, ME ; Steele, AM ; Saito, M.; Hacker, BJ ; Evers, BM ; Saito, H. "A new cecal slurry preparation protocol with improved long-term reproducibility for animal models of sepsis." PloS one 9, 12 (2014): e115705. [PubMed Link] | [ Full text ]
Wu, Y.; Wang, Y.; Yang, XH ; Kang, T.; Zhao, Y.; Wang, C.; Evers, BM ; Zhou, BP "The deubiquitinase USP28 stabilizes LSD1 and confers stem-cell-like traits to breast cancer cells." Cell reports 5, 1 (2013): 224-36. [PubMed Link] | [ Full text ]
Hollis, CP ; Weiss, HL ; Leggas, M.; Evers, BM ; Gemeinhart, RA ; Li, T. "Biodistribution and bioimaging studies of hybrid paclitaxel nanocrystals: lessons learned of the EPR effect and image-guided drug delivery." Journal of controlled release : official journal of the Controlled Release Society 172, 1 (2013): 12-21. [PubMed Link] | [ Full text ]
Wang, S.; Haque, F.; Rychahou, PG ; Evers, BM ; Guo, P. "Engineered nanopore of Phi29 DNA-packaging motor for real-time detection of single colon cancer specific antibody in serum." ACS nano 7, 11 (2013): 9814-22. [PubMed Link] | [ Full text ]
Gedaly, R.; Galuppo, R.; Musgrave, Y.; Angulo, P.; Hundley, J.; Shah, M.; Daily, MF ; Chen, C.; Cohen, DA ; Spear, BT ; Evers, BM "PKI-587 and sorafenib alone and in combination on inhibition of liver cancer stem cell proliferation." The Journal of surgical research 185, 1 (2013): 225-30. [PubMed Link] | [ Full text ]
Kim, JT ; Li, J.; Jang, ER ; Gulhati, P.; Rychahou, PG ; Napier, DL ; Wang, C.; Weiss, HL ; Lee, EY ; Anthony, L.; Townsend CM, Jr ; Liu, C.; Evers, BM "Deregulation of Wnt/β-catenin signaling through genetic or epigenetic alterations in human neuroendocrine tumors." Carcinogenesis 34, 5 (2013): 953-61. [PubMed Link] | [ Full text ]
Dong, C.; Yuan, T.; Wu, Y.; Wang, Y.; Fan, TW ; Miriyala, S.; Lin, Y.; Yao, J.; Shi, J.; Kang, T.; Lorkiewicz, P.; St Clair, D.; Hung, MC ; Evers, BM ; Zhou, BP "Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer." Cancer cell 23, 3 (2013): 316-31. [PubMed Link] | [ Full text ]
Dong, C.; Wu, Y.; Wang, Y.; Wang, C.; Kang, T.; Rychahou, PG ; Chi, YI ; Evers, BM ; Zhou, BP "Interaction with Suv39H1 is critical for Snail-mediated E-cadherin repression in breast cancer." Oncogene 32, 11 (2013): 1351-62. [PubMed Link] | [ Full text ]
Li, X.; Zhou, Q.; Sunkara, M.; Kutys, ML ; Wu, Z.; Rychahou, P.; Morris, AJ ; Zhu, H.; Evers, BM ; Huang, C. "Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I γ by HECTD1 regulates focal adhesion dynamics and cell migration." Journal of cell science 126, Pt 12 (2013): 2617-28. [PubMed Link] | [ Full text ]
Wang, Q.; Zhou, Y.; Rychahou, P.; Liu, C.; Weiss, HL ; Evers, BM "NFAT5 represses canonical Wnt signaling via inhibition of β-catenin acetylation and participates in regulating intestinal cell differentiation." Cell death & disease 4, (2013): e671. [PubMed Link] | [ Full text ]
Li, X.; Stevens, PD ; Yang, H.; Gulhati, P.; Wang, W.; Evers, BM ; Gao, T. "The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer." Oncogene 32, 4 (2013): 471-8. [PubMed Link] | [ Full text ]
Valentino, JD ; Rychahou, PG ; Mustain, WC ; Elliott, VA ; Evers, BM "Murine portal vein catheterization to analyze liver-directed therapies." The Journal of surgical research 185, 2 (2013): 690-6. [PubMed Link] | [ Full text ]
Zhang, W.; Sviripa, V.; Chen, X.; Shi, J.; Yu, T.; Hamza, A.; Ward, ND ; Kril, LM ; Vander Kooi, CW ; Zhan, CG ; Evers, BM ; Watt, DS ; Liu, C. "Fluorinated N,N-dialkylaminostilbenes repress colon cancer by targeting methionine S-adenosyltransferase 2A." ACS chemical biology 8, 4 (2013): 796-803. [PubMed Link] | [ Full text ]
Starr, ME ; Hu, Y.; Stromberg, AJ ; Carmical, JR ; Wood, TG ; Evers, BM ; Saito, H. "Gene expression profile of mouse white adipose tissue during inflammatory stress: age-dependent upregulation of major procoagulant factors." Aging cell 12, 2 (2013): 194-206. [PubMed Link] | [ Full text ]
Mustain, WC ; Starr, ME ; Valentino, JD ; Cohen, DA ; Okamura, D.; Wang, C.; Evers, BM ; Saito, H. "Inflammatory cytokine gene expression in mesenteric adipose tissue during acute experimental colitis." PloS one 8, 12 (2013): e83693. [PubMed Link] | [ Full text ]
Gulhati, P.; Zaytseva, YY ; Valentino, JD ; Stevens, PD ; Kim, JT ; Sasazuki, T.; Shirasawa, S.; Lee, EY ; Weiss, HL ; Dong, J.; Gao, T.; Evers, BM "Sorafenib enhances the therapeutic efficacy of rapamycin in colorectal cancers harboring oncogenic KRAS and PIK3CA." Carcinogenesis 33, 9 (2012): 1782-90. [PubMed Link] | [ Full text ]
Okamura, D.; Starr, ME ; Lee, EY ; Stromberg, AJ ; Evers, BM ; Saito, H. "Age-dependent vulnerability to experimental acute pancreatitis is associated with increased systemic inflammation and thrombosis." Aging cell 11, 5 (2012): 760-9. [PubMed Link] | [ Full text ]
Zaytseva, YY ; Rychahou, PG ; Gulhati, P.; Elliott, VA ; Mustain, WC ; O'Connor, K.; Morris, AJ ; Sunkara, M.; Weiss, HL ; Lee, EY ; Evers, BM "Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer." Cancer research 72, 6 (2012): 1504-17. [PubMed Link] | [ Full text ]
Zaytseva, YY ; Valentino, JD ; Gulhati, P.; Evers, BM "mTOR inhibitors in cancer therapy." Cancer letters 319, 1 (2012): 1-7. [PubMed Link] | [ Full text ]
Wang, X.; Mandal, AK ; Saito, H.; Pulliam, JF ; Lee, EY ; Ke, ZJ ; Lü, J.; Ding, S.; Li, L.; Shelton, BJ ; Tucker, T.; Evers, BM ; Zhang, Z.; Shi, X. "Arsenic and chromium in drinking water promote tumorigenesis in a mouse colitis-associated colorectal cancer model and the potential mechanism is ROS-mediated Wnt/β-catenin signaling pathway." Toxicology and applied pharmacology 262, 1 (2012): 11-21. [PubMed Link] | [ Full text ]
Gedaly, R.; Angulo, P.; Chen, C.; Creasy, KT ; Spear, BT ; Hundley, J.; Daily, MF ; Shah, M.; Evers, BM "The role of PI3K/mTOR inhibition in combination with sorafenib in hepatocellular carcinoma treatment." Anticancer research 32, 7 (2012): 2531-6. [PubMed Link] | [ Full text ]
Yu, T.; Chen, X.; Zhang, W.; Colon, D.; Shi, J.; Napier, D.; Rychahou, P.; Lu, W.; Lee, EY ; Weiss, HL ; Evers, BM ; Liu, C. "Regulation of the potential marker for intestinal cells, Bmi1, by β-catenin and the zinc finger protein KLF4: implications for colon cancer." The Journal of biological chemistry 287, 6 (2012): 3760-8. [PubMed Link] | [ Full text ]
Guo, Z.; Zhou, Y.; Evers, BM ; Wang, Q. "Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer cells." Biochemical and biophysical research communications 418, 2 (2012): 426-32. [PubMed Link] | [ Full text ]
Haque, F.; Shu, D.; Shu, Y ; Shlyakhtenko, LS ; Rychahou, PG ; Evers, BM ; Guo, P. "Ultrastable synergistic tetravalent RNA nanoparticles for targeting to cancers." Nano today 7, 4 (2012): 245-257. [PubMed Link] |
Valentino, JD ; Elliott, VA ; Zaytseva, YY ; Rychahou, PG ; Mustain, WC ; Wang, C.; Gao, T.; Evers, BM "Novel small interfering RNA cotargeting strategy as treatment for colorectal cancer." Surgery 152, 2 (2012): 277-85. [PubMed Link] | [ Full text ]
Li, J.; Song, J.; Cassidy, MG ; Rychahou, P.; Starr, ME ; Liu, J.; Li, X.; Epperly, G.; Weiss, HL ; Townsend CM, Jr ; Gao, T.; Evers, BM "PI3K p110α/Akt signaling negatively regulates secretion of the intestinal peptide neurotensin through interference of granule transport." Molecular endocrinology (Baltimore, Md.) 26, 8 (2012): 1380-93. [PubMed Link] | [ Full text ]
Zhou, Y.; Wang, Q.; Guo, Z.; Weiss, HL ; Evers, BM "Nuclear factor of activated T-cell c3 inhibition of mammalian target of rapamycin signaling through induction of regulated in development and DNA damage response 1 in human intestinal cells." Molecular biology of the cell 23, 15 (2012): 2963-72. [PubMed Link] | [ Full text ]
Gedaly, R.; Angulo, P.; Hundley, J.; Daily, MF ; Chen, C.; Evers, BM "PKI-587 and sorafenib targeting PI3K/AKT/mTOR and Ras/Raf/MAPK pathways synergistically inhibit HCC cell proliferation." The Journal of surgical research 176, 2 (2012): 542-8. [PubMed Link] | [ Full text ]
Xiong, G.; Wang, C.; Evers, BM ; Zhou, BP ; Xu, R. "RORα suppresses breast tumor invasion by inducing SEMA3F expression." Cancer research 72, 7 (2012): 1728-39. [PubMed Link] | [ Full text ]
Dong, C.; Wu, Y.; Yao, J.; Wang, Y.; Yu, Y.; Rychahou, PG ; Evers, BM ; Zhou, BP "G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer." The Journal of clinical investigation 122, 4 (2012): 1469-86. [PubMed Link] | [ Full text ]
Takahashi, H.; Okamura, D.; Starr, ME ; Saito, H.; Evers, BM "Age-dependent reduction of the PI3K regulatory subunit p85α suppresses pancreatic acinar cell proliferation." Aging cell 11, 2 (2012): 305-14. [PubMed Link] | [ Full text ]
Gulhati, P.; Bowen, KA ; Liu, J.; Stevens, PD ; Rychahou, PG ; Chen, M.; Lee, EY ; Weiss, HL ; O'Connor, KL ; Gao, T.; Evers, BM "mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways." Cancer research 71, 9 (2011): 3246-56. [PubMed Link] | [ Full text ]
Zhang, W.; Sviripa, V.; Kril, LM ; Chen, X.; Yu, T.; Shi, J.; Rychahou, P.; Evers, BM ; Watt, DS ; Liu, C. "Fluorinated N,N-dialkylaminostilbenes for Wnt pathway inhibition and colon cancer repression." Journal of medicinal chemistry 54, 5 (2011): 1288-97. [PubMed Link] | [ Full text ]
Li, J.; Liu, J.; Song, J.; Wang, X.; Weiss, HL ; Townsend CM, Jr ; Gao, T.; Evers, BM "mTORC1 inhibition increases neurotensin secretion and gene expression through activation of the MEK/ERK/c-Jun pathway in the human endocrine cell line BON." American journal of physiology. Cell physiology 301, 1 (2011): C213-26. [PubMed Link] | [ Full text ]
Wang, Q.; Zhou, Y.; Jackson, LN ; Johnson, SM ; Chow, CW ; Evers, BM "Nuclear factor of activated T cells (NFAT) signaling regulates PTEN expression and intestinal cell differentiation." Molecular biology of the cell 22, 3 (2011): 412-20. [PubMed Link] | [ Full text ]
Mustain, WC ; Rychahou, PG ; Evers, BM "The role of neurotensin in physiologic and pathologic processes." Current opinion in endocrinology, diabetes, and obesity 18, 1 (2011): 75-82. [PubMed Link] | [ Full text ]
Silva, SR ; Zaytseva, YY ; Jackson, LN ; Lee, EY ; Weiss, HL ; Bowen, KA ; Townsend CM, Jr ; Evers, BM "The effect of PTEN on serotonin synthesis and secretion from the carcinoid cell line BON." Anticancer research 31, 4 (2011): 1153-60. [PubMed Link] | [ Full text ]
Valentino, J.; Evers, BM "Recent advances in the diagnosis and treatment of gastrointestinal carcinoids." Advances in surgery 45, (2011): 285-300. [PubMed Link] | [ Full text ]
Wang, Q.; Zhou, Y.; Weiss, HL ; Chow, CW ; Evers, BM "NFATc1 regulation of TRAIL expression in human intestinal cells." PloS one 6, 5 (2011): e19882. [PubMed Link] | [ Full text ]
Lin, Y.; Wu, Y.; Li, J.; Dong, C.; Ye, X.; Chi, YI ; Evers, BM ; Zhou, BP "The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1." The EMBO journal 29, 11 (2010): 1803-16. [PubMed Link] | [ Full text ]
Gedaly, R.; Angulo, P.; Hundley, J.; Daily, MF ; Chen, C.; Koch, A.; Evers, BM "PI-103 and sorafenib inhibit hepatocellular carcinoma cell proliferation by blocking Ras/Raf/MAPK and PI3K/AKT/mTOR pathways." Anticancer research 30, 12 (2010): 4951-8. [PubMed Link] | [ Full text ]
Bowen, KA ; Doan, HQ ; Zhou, BP ; Wang, Q.; Zhou, Y.; Rychahou, PG ; Evers, BM "PTEN loss induces epithelial--mesenchymal transition in human colon cancer cells." Anticancer research 29, 11 (2009): 4439-49. [PubMed Link] | [ Full text ]
Gulhati, P.; Cai, Q.; Li, J.; Liu, J.; Rychahou, PG ; Qiu, S.; Lee, EY ; Silva, SR ; Bowen, KA ; Gao, T.; Evers, BM "Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer." Clinical cancer research : an official journal of the American Association for Cancer Research 15, 23 (2009): 7207-16. [PubMed Link] | [ Full text ]
Evers, BM ; Mullins, RJ ; Matthews, TH ; Broghamer, WL ; Polk HC, Jr "Multiple adenocarcinomas of the colon and rectum. An analysis of incidences and current trends." Diseases of the colon and rectum 31, 7 (1988): 518-22. [PubMed Link] |
Malangoni, MA ; Evers, BM ; Peyton, JC ; Wellhausen, SR "Reticuloendothelial clearance and splenic mononuclear cell populations after resection and autotransplantation." American journal of surgery 155, 2 (1988): 298-302. [PubMed Link] | [ Full text ]